Serine-phosphoethanolamine synthase

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In enzymology, a serine-phosphoethanolamine synthase (EC 2.7.8.4) is an enzyme that catalyzes the chemical reaction

CDP-ethanolamine + L-serine CMP + L-serine-phosphoethanolamine

Thus, the two substrates of this enzyme are CDP-ethanolamine and L-serine, whereas its two products are CMP and L-serine-phosphoethanolamine.

This enzyme belongs to the family of transferases, specifically those transferring non-standard substituted phosphate groups. The systematic name of this enzyme class is CDP-ethanolamine:L-serine ethanolamine phosphotransferase. Other names in common use include serine ethanolamine phosphate synthetase, serine ethanolamine phosphodiester synthase, serine ethanolaminephosphotransferase, serine-phosphinico-ethanolamine synthase, and serinephosphoethanolamine synthase. This enzyme participates in glycerophospholipid metabolism.

[edit] References

• IUBMB entry for 2.7.8.4
• BRENDA references for 2.7.8.4 (Recommended.)
• PubMed references for 2.7.8.4
• PubMed Central references for 2.7.8.4
• Google Scholar references for 2.7.8.4
• Allen AK, Rosenberg H (1968). "The mechanism of action and some properties of serine ethanolamine phosphate synthetase". Biochim. Biophys. Acta. 151: 504–19. PMID 5636380. 

[edit] External links

The CAS registry number for this enzyme class is 9023-23-8.

• IUBMB entry for 2.7.8.4

• KEGG entry for 2.7.8.4

• BRENDA entry for 2.7.8.4

• NiceZyme view of 2.7.8.4

• EC2PDB: PDB structures for 2.7.8.4

• PRIAM entry for 2.7.8.4

• PUMA2 entry for 2.7.8.4

• IntEnz: Integrated Enzyme entry for 2.7.8.4

• MetaCyc entry for 2.7.8.4

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047494: serine-phosphoethanolamine synthase

• AMIGO entry for GO code 0047494: serine-phosphoethanolamine synthase