SEPT8

From Wikipedia, the free encyclopedia

Septin 8

Identifiers

SEPT8; SEP2; KIAA0202

External IDs

Gene ontology
Molecular Function:	• nucleotide binding • protein binding • GTP binding
Biological Process:	• cell cycle

Orthologs

Human

Mouse

Entrez

23176

n/a

Refseq

XM_034872 (mRNA)
XP_034872 (protein)

n/a (mRNA)
n/a (protein)

Pubmed search

[1]

n/a

Septin 8, also known as SEPT8, is a human gene.^[1]

SEPT8 is a member of the highly conserved septin family. Septins are 40- to 60-kD GTPases that assemble as filamentous scaffolds. They are involved in the organization of submembranous structures, in neuronal polarity, and in vesicle trafficking (Blaser et al., 2003).[supplied by OMIM]^[1]

[edit] References

^ ^a ^b Entrez Gene: SEPT8 septin 8.

[edit] Further reading

Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery.". Genome Res. 6 (9): 791–806. PMID 8889548.
Nagase T, Seki N, Ishikawa K, et al. (1997). "Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain.". DNA Res. 3 (5): 321–9, 341–54. PMID 9039502.
Frazer KA, Ueda Y, Zhu Y, et al. (1997). "Computational and biological analysis of 680 kb of DNA sequence from the human 5q31 cytokine gene cluster region.". Genome Res. 7 (5): 495–512. PMID 9149945.
Wenderfer SE, Slack JP, McCluskey TS, Monaco JJ (2000). "Identification of 40 genes on a 1-Mb contig around the IL-4 cytokine family gene cluster on mouse chromosome 11.". Genomics 63 (3): 354–73. doi:10.1006/geno.1999.6100. PMID 10704283.
Bläser S, Jersch K, Hainmann I, et al. (2002). "Human septin-septin interaction: CDCrel-1 partners with KIAA0202.". FEBS Lett. 519 (1-3): 169–72. PMID 12023038.
Yang T, Gao YK, Chen JY (2002). "KIAA0202, a human septin family member, interacting with hPFTAIRE1.". Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao 34 (4): 520–5. PMID 12098780.
Macara IG, Baldarelli R, Field CM, et al. (2003). "Mammalian septins nomenclature.". Mol. Biol. Cell 13 (12): 4111–3. doi:10.1091/mbc.E02-07-0438. PMID 12475938.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
Bläser S, Jersch K, Hainmann I, et al. (2003). "Isolation of new splice isoforms, characterization and expression analysis of the human septin SEPT8 (KIAA0202).". Gene 312: 313–20. PMID 12909369.
Bläser S, Horn J, Würmell P, et al. (2004). "The novel human platelet septin SEPT8 is an interaction partner of SEPT4.". Thromb. Haemost. 91 (5): 959–66. doi:10.1267/THRO04050959. PMID 15116257.
Martínez C, Sanjuan MA, Dent JA, et al. (2005). "Human septin-septin interactions as a prerequisite for targeting septin complexes in the cytosol.". Biochem. J. 382 (Pt 3): 783–91. doi:10.1042/BJ20040372. PMID 15214843.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes.". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMID 16344560.
Bläser S, Röseler S, Rempp H, et al. (2006). "Human endothelial cell septins: SEPT11 is an interaction partner of SEPT5.". J. Pathol. 210 (1): 103–10. doi:10.1002/path.2013. PMID 16767699.
Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry.". Mol. Syst. Biol. 3: 89. doi:10.1038/msb4100134. PMID 17353931.
Xin X, Pache M, Zieger B, et al. (2007). "Septin expression in proliferative retinal membranes.". J. Histochem. Cytochem. 55 (11): 1089–94. doi:10.1369/jhc.7A7188.2007. PMID 17625225.