SEMA4C

From Wikipedia, the free encyclopedia

Sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C

Identifiers

SEMA4C; FLJ20369; KIAA1739; M-SEMA-F; M-Sema F; MGC126382; MGC126383; SEMAI; Semacl1; Semaf

External IDs

OMIM: 604462 MGI: 109252 HomoloGene: 23047

Gene ontology
Molecular Function:	• receptor activity
Cellular Component:	• membrane • integral to membrane
Biological Process:	• multicellular organismal development • nervous system development • cell differentiation

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_017789 (mRNA)
NP_060259 (protein)

XM_898566 (mRNA)
XP_903659 (protein)

Location

Chr 2: 96.89 - 96.9 Mb

Chr 1: 36.49 - 36.5 Mb

Pubmed search

[1]

[2]

Sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C, also known as SEMA4C, is a human gene.^[1]

[edit] References

^ Entrez Gene: SEMA4C sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C.

[edit] Further reading

Inagaki S, Furuyama T, Iwahashi Y (1995). "Identification of a member of mouse semaphorin family.". FEBS Lett. 370 (3): 269–72. PMID 7656991.
Simmons AD, Püschel AW, McPherson JD, et al. (1998). "Molecular cloning and mapping of human semaphorin F from the Cri-du-chat candidate interval.". Biochem. Biophys. Res. Commun. 242 (3): 685–91. doi:10.1006/bbrc.1997.8027. PMID 9464278.
Wang LH, Kalb RG, Strittmatter SM (1999). "A PDZ protein regulates the distribution of the transmembrane semaphorin, M-SemF.". J. Biol. Chem. 274 (20): 14137–46. PMID 10318831.
Inagaki S, Ohoka Y, Sugimoto H, et al. (2001). "Sema4c, a transmembrane semaphorin, interacts with a post-synaptic density protein, PSD-95.". J. Biol. Chem. 276 (12): 9174–81. doi:10.1074/jbc.M009051200. PMID 11134026.
Ohoka Y, Hirotani M, Sugimoto H, et al. (2001). "Semaphorin 4C, a transmembrane semaphorin, [corrected] associates with a neurite-outgrowth-related protein, SFAP75.". Biochem. Biophys. Res. Commun. 280 (1): 237–43. doi:10.1006/bbrc.2000.4080. PMID 11162505.
Nagase T, Kikuno R, Hattori A, et al. (2001). "Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.". DNA Res. 7 (6): 347–55. PMID 11214970.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
Clark HF, Gurney AL, Abaya E, et al. (2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMID 12975309.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.