SEGPHOS
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| SEGPHOS | |
|---|---|
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| IUPAC name | 5,5′-Bis(diphenylphosphino)-4,4′-bi-1,3-benzodioxole |
| Other names | SEGPHOS |
| Identifiers | |
| CAS number | [244261-66-3] (R) [210169-54-3] (S) |
| Properties | |
| Molecular formula | C38H28O4P2 |
| Molar mass | 610.57 g/mol |
| Appearance | colorless solid |
| Solubility in water | organic solvents |
| Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) Infobox disclaimer and references |
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SEGPHOS is a chiral ligand that is used in asymmetric synthesis.[1] It was developed after BINAP and was investigated since it has a narrower dihedral angle between the aromatic faces. This was predicted and then confirmed to increase the enantioselectivity and activity of metal complexes of SEGPHOS.
[edit] References
- ^ Shimizu, H., Nagasaki, I., Matsumura, K., Sayo, N., Saito, T. (2007). "Developments in Asymmetric Hydrogenation from an Industrial Perspective". Acc. Chem. Res. 40: 1385–1393. doi:.
