SEC22A

From Wikipedia, the free encyclopedia

SEC22 vesicle trafficking protein homolog A (S. cerevisiae)

Identifiers

SEC22A; SEC22L2

External IDs

Gene ontology
Molecular Function:	• transporter activity
Cellular Component:	• endoplasmic reticulum • endoplasmic reticulum membrane • membrane • integral to membrane
Biological Process:	• ER to Golgi vesicle-mediated transport • protein transport • vesicle-mediated transport

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_012430 (mRNA)
NP_036562 (protein)

NM_133704 (mRNA)
NP_598465 (protein)

Location

Chr 3: 124.4 - 124.47 Mb

Chr 16: 35.23 - 35.28 Mb

Pubmed search

[1]

[2]

SEC22 vesicle trafficking protein homolog A (S. cerevisiae), also known as SEC22A, is a human gene.^[1]

The protein encoded by this gene belongs to the member of the SEC22 family of vesicle trafficking proteins. This protein has similarity to rat SEC22 and may act in the early stages of the secretory pathway. There is evidence for the use of multiple poly A sites in this gene.^[1]

[edit] References

^ ^a ^b Entrez Gene: SEC22A SEC22 vesicle trafficking protein homolog A (S. cerevisiae).

[edit] Further reading

Hay JC, Hirling H, Scheller RH (1996). "Mammalian vesicle trafficking proteins of the endoplasmic reticulum and Golgi apparatus.". J. Biol. Chem. 271 (10): 5671–9. PMID 8621431.
Hay JC, Chao DS, Kuo CS, Scheller RH (1997). "Protein interactions regulating vesicle transport between the endoplasmic reticulum and Golgi apparatus in mammalian cells.". Cell 89 (1): 149–58. PMID 9094723.
Tang BL, Low DY, Hong W (1998). "Hsec22c: a homolog of yeast Sec22p and mammalian rsec22a and msec22b/ERS-24.". Biochem. Biophys. Res. Commun. 243 (3): 885–91. doi:10.1006/bbrc.1998.8194. PMID 9501016.
Zhang QH, Ye M, Wu XY, et al. (2001). "Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells.". Genome Res. 10 (10): 1546–60. PMID 11042152.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes.". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMID 16344560.
Mancias JD, Goldberg J (2007). "The transport signal on Sec22 for packaging into COPII-coated vesicles is a conformational epitope.". Mol. Cell 26 (3): 403–14. doi:10.1016/j.molcel.2007.03.017. PMID 17499046.