SCGB2A2 (gene)

From Wikipedia, the free encyclopedia

Secretoglobin, family 2A, member 2

Identifiers

SCGB2A2; MGB1; UGB2

External IDs

Gene ontology
Molecular Function:	• molecular_function • steroid binding
Cellular Component:	• cellular_component
Biological Process:	• biological_process

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

n/a

n/a

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Refseq

NM_002411 (mRNA)
NP_002402 (protein)

n/a (mRNA)
n/a (protein)

Location

Chr 11: 61.79 - 61.8 Mb

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Pubmed search

[1]

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Secretoglobin, family 2A, member 2, also known as SCGB2A2, is a human gene.^[1]

[edit] References

^ Entrez Gene: SCGB2A2 secretoglobin, family 2A, member 2.

[edit] Further reading

Watson MA, Fleming TP (1996). "Mammaglobin, a mammary-specific member of the uteroglobin gene family, is overexpressed in human breast cancer.". Cancer Res. 56 (4): 860-5. PMID 8631025.
Wilson PC, de Bouteiller O, Liu YJ, et al. (1998). "Somatic hypermutation introduces insertions and deletions into immunoglobulin V genes.". J. Exp. Med. 187 (1): 59-70. PMID 9419211.
Watson MA, Darrow C, Zimonjic DB, et al. (1998). "Structure and transcriptional regulation of the human mammaglobin gene, a breast cancer associated member of the uteroglobin gene family localized to chromosome 11q13.". Oncogene 16 (6): 817-24. doi:10.1038/sj.onc.1201597. PMID 9488047.
Fischer M, Küppers R (1998). "Human IgA- and IgM-secreting intestinal plasma cells carry heavily mutated VH region genes.". Eur. J. Immunol. 28 (9): 2971-7. PMID 9754584.
Carter D, Douglass JF, Cornellison CD, et al. (2002). "Purification and characterization of the mammaglobin/lipophilin B complex, a promising diagnostic marker for breast cancer.". Biochemistry 41 (21): 6714-22. PMID 12022875.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
Izmailova E, Bertley FM, Huang Q, et al. (2003). "HIV-1 Tat reprograms immature dendritic cells to express chemoattractants for activated T cells and macrophages.". Nat. Med. 9 (2): 191-7. doi:10.1038/nm822. PMID 12539042.
Cerveira N, Torres L, Rocha P, et al. (2004). "Highly sensitive detection of the MGB1 transcript (mammaglobin) in the peripheral blood of breast cancer patients.". Int. J. Cancer 108 (4): 592-5. doi:10.1002/ijc.11609. PMID 14696125.
Ouellette RJ, Richard D, Maïcas E (2004). "RT-PCR for mammaglobin genes, MGB1 and MGB2, identifies breast cancer micrometastases in sentinel lymph nodes.". Am. J. Clin. Pathol. 121 (5): 637-43. doi:10.1309/MMAC-TXT5-5L8Q-TKC1. PMID 15151203.
Ferrucci PF, Rabascio C, Mazzetta C, et al. (2005). "Mammaglobin expression in leukapheresis products is a predictive marker of poor prognosis in women with high-risk breast cancer.". Clin. Cancer Res. 10 (18 Pt 1): 6039-46. doi:10.1158/1078-0432.CCR-03-0453. PMID 15447988.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334.
O'Brien NA, O'Donovan N, Ryan B, et al. (2005). "Mammaglobin a in breast cancer: existence of multiple molecular forms.". Int. J. Cancer 114 (4): 623-7. doi:10.1002/ijc.20780. PMID 15609337.
Roncella S, Ferro P, Bacigalupo B, et al. (2005). "Human mammaglobin mRNA is a reliable molecular marker for detecting occult breast cancer cells in peripheral blood.". J. Exp. Clin. Cancer Res. 24 (2): 265-71. PMID 16110760.
Span PN, Sweep FC (2006). "Mammaglobin as molecular marker of breast cancer (micro)metastases.". Clin. Cancer Res. 11 (19 Pt 1): 7043; author reply 7044. doi:10.1158/1078-0432.CCR-05-1378. PMID 16203799.
Roncella S, Ferro P, Bacigalupo B, et al. (2006). "Relationship between human mammaglobin mRNA expression in breast cancer tissue and clinico-pathologic features of the tumors.". J. Exp. Clin. Cancer Res. 25 (1): 65-72. PMID 16761620.
Ntoulia M, Stathopoulou A, Ignatiadis M, et al. (2007). "Detection of Mammaglobin A-mRNA-positive circulating tumor cells in peripheral blood of patients with operable breast cancer with nested RT-PCR.". Clin. Biochem. 39 (9): 879-87. doi:10.1016/j.clinbiochem.2006.06.009. PMID 16925986.
Gimbergues P, Dauplat MM, Cayre A, et al. (2007). "Correlation between molecular metastases in sentinel lymph nodes of breast cancer patients and St Gallen risk category.". Eur J Surg Oncol 33 (1): 16-22. doi:10.1016/j.ejso.2006.09.013. PMID 17071045.
Sasaki E, Tsunoda N, Hatanaka Y, et al. (2007). "Breast-specific expression of MGB1/mammaglobin: an examination of 480 tumors from various organs and clinicopathological analysis of MGB1-positive breast cancers.". Mod. Pathol. 20 (2): 208-14. doi:10.1038/modpathol.3800731. PMID 17192791.