Talk:Saccharomyces boulardii

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[edit] Distinct strain?

Interesting article suggests S. boulardii is not a distinct strain:

Species identification and virulence attributes of Saccharomyces boulardii (nom. inval.). J Clin Microbiol. 1998 Sep;36(9):2613-7. McCullough MJ, Clemons KV, McCusker JH, Stevens DA.

from article: The results of the present study show that these S. boulardii strains are asporogenous strains of the species S. cerevisiae, not representatives of a distinct and separate species, and possess moderate virulence in murine models of systemic infection. Therefore, caution should be advised in the clinical use of these strains in immunocompromised patients until further study is undertaken.

Abstract.—Preceding unsigned comment added by Mfbabcock (talkcontribs)

This is an interesting topic...is S. boulardii really a separate species from S. cerevisiae?
  • McCullough MJ, Clemons KV, McCusker JH, Stevens DA (1998). "Species identification and virulence attributes of Saccharomyces boulardii (nom. inval.)". J. Clin. Microbiol. 36 (9): 2613–7. PMID 9705402.  (above)
  • van der Aa Kühle A, Jespersen L (2003). "The taxonomic position of Saccharomyces boulardii as evaluated by sequence analysis of the D1/D2 domain of 26S rDNA, the ITS1-5.8S rDNA-ITS2 region and the mitochondrial cytochrome-c oxidase II gene". Syst. Appl. Microbiol. 26 (4): 564–71. PMID 14666985. 
  • Mitterdorfer G, Mayer HK, Kneifel W, Viernstein H (2002). "Clustering of Saccharomyces boulardii strains within the species S. cerevisiae using molecular typing techniques". J. Appl. Microbiol. 93 (4): 521–30. PMID 12234334. 
  • McFarland LV (1996). "Saccharomyces boulardii is not Saccharomyces cerevisiae". Clin. Infect. Dis. 22 (1): 200–1. PMID 8825013. 
I think it merits further investigation and inclusion within the article. — Scientizzle 21:06, 11 January 2008 (UTC)

[edit] Cleanup time...

I've already started to clean this article up. It looks to me like it was written by a rep from a probiotic company...Additionally, I've had a difficult time locating some of the references listed in the article: they're not on PubMed the way they're cited, which concerns me. — Scientizzle 20:47, 11 January 2008 (UTC)

Interesting studies to consider including...
  • "Invasive infections due to Saccharomyces boulardii (Ultra-levure)" (2007). Prescrire Int 16 (89): 110. PMID 17582930. 
  • Herbrecht R, Nivoix Y (2005). "Saccharomyces cerevisiae fungemia: an adverse effect of Saccharomyces boulardii probiotic administration". Clin. Infect. Dis. 40 (11): 1635–7. doi:10.1086/429926. PMID 15889361. 
  • Enache-Angoulvant A, Hennequin C (2005). "Invasive Saccharomyces infection: a comprehensive review". Clin. Infect. Dis. 41 (11): 1559–68. doi:10.1086/497832. PMID 16267727. 
  • Szajewska H, Mrukowicz J (2005). "Meta-analysis: non-pathogenic yeast Saccharomyces boulardii in the prevention of antibiotic-associated diarrhoea". Aliment. Pharmacol. Ther. 22 (5): 365–72. doi:10.1111/j.1365-2036.2005.02624.x. PMID 16128673. 
  • Burkhardt O, Köhnlein T, Pletz M, Welte T (2005). "Saccharomyces boulardii induced sepsis: successful therapy with voriconazole after treatment failure with fluconazole". Scand. J. Infect. Dis. 37 (1): 69–72. doi:10.1080/00365540510026454. PMID 15764194. 
  • Johnston BC, Supina AL, Ospina M, Vohra S (2007). "Probiotics for the prevention of pediatric antibiotic-associated diarrhea". Cochrane Database Syst Rev (2): CD004827. doi:10.1002/14651858.CD004827.pub2. PMID 17443557. 
  • Vandenplas Y, Salvatore S, Viera M, Devreker T, Hauser B (2007). "Probiotics in infectious diarrhoea in children: are they indicated?". Eur. J. Pediatr. 166 (12): 1211–8. doi:10.1007/s00431-007-0497-9. PMID 17611775. 
  • McFarland LV (2007). "Meta-analysis of probiotics for the prevention of traveler's diarrhea". Travel Med Infect Dis 5 (2): 97–105. doi:10.1016/j.tmaid.2005.10.003. PMID 17298915.