RTN3

From Wikipedia, the free encyclopedia


Reticulon 3
Identifiers
Symbol(s) RTN3; HAP; ASYIP; NSPL2; NSPLII; RTN3-A1
External IDs OMIM: 604249 MGI: 1339970 HomoloGene: 24934
RNA expression pattern

More reference expression data
Orthologs
Human Mouse
Entrez 10313 20168
Ensembl ENSG00000133318 ENSMUSG00000024758
Uniprot O95197 Q3UF62
Refseq NM_006054 (mRNA)
NP_006045 (protein)		 NM_001003930 (mRNA)
NP_001003930 (protein)
Location Chr 11: 63.21 - 63.28 Mb Chr 19: 7.49 - 7.55 Mb
Pubmed search [1] [2]

Reticulon 3, also known as RTN3, is a human gene.[1]

The reticulons are a group of highly conserved genes with preferential expression in neuroendocrine tissues (see, e.g., RTN1; MIM 600865).[supplied by OMIM][1]

[edit] References

  1. ^ a b Entrez Gene: RTN3 reticulon 3.

[edit] Further reading

  • Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.". Gene 138 (1-2): 171–4. PMID 8125298. 
  • Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.". Gene 200 (1-2): 149–56. PMID 9373149. 
  • Moreira EF, Jaworski CJ, Rodriguez IR (1999). "Cloning of a novel member of the reticulon gene family (RTN3): gene structure and chromosomal localization to 11q13.". Genomics 58 (1): 73–81. doi:10.1006/geno.1999.5807. PMID 10331947. 
  • Qu X, Qi Y, Qi B (2002). "Generation of multiple mRNA transcripts from the novel human apoptosis-inducing gene hap by alternative polyadenylation utilization and the translational activation function of 3' untranslated region.". Arch. Biochem. Biophys. 400 (2): 233–44. doi:10.1016/S0003-9861(02)00016-4. PMID 12054434. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Qi B, Qi Y, Watari A, et al. (2003). "Pro-apoptotic ASY/Nogo-B protein associates with ASYIP.". J. Cell. Physiol. 196 (2): 312–8. doi:10.1002/jcp.10297. PMID 12811824. 
  • Oertle T, Klinger M, Stuermer CA, Schwab ME (2003). "A reticular rhapsody: phylogenic evolution and nomenclature of the RTN/Nogo gene family.". FASEB J. 17 (10): 1238–47. doi:10.1096/fj.02-1166hyp. PMID 12832288. 
  • Di Sano F, Fazi B, Citro G, et al. (2003). "Glucosylceramide synthase and its functional interaction with RTN-1C regulate chemotherapeutic-induced apoptosis in neuroepithelioma cells.". Cancer Res. 63 (14): 3860–5. PMID 12873973. 
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039. 
  • Huang X, Yang H, Zhou Y, et al. (2004). "Overexpression of human reticulon 3 (hRTN3) in astrocytoma.". Clin. Neuropathol. 23 (1): 1–7. PMID 14986927. 
  • Hu Y, Fang X, Dunham SM, et al. (2004). "90-kDa ribosomal S6 kinase is a direct target for the nuclear fibroblast growth factor receptor 1 (FGFR1): role in FGFR1 signaling.". J. Biol. Chem. 279 (28): 29325–35. doi:10.1074/jbc.M311144200. PMID 15117958. 
  • He W, Lu Y, Qahwash I, et al. (2004). "Reticulon family members modulate BACE1 activity and amyloid-beta peptide generation.". Nat. Med. 10 (9): 959–65. doi:10.1038/nm1088. PMID 15286784. 
  • Di Scala F, Dupuis L, Gaiddon C, et al. (2005). "Tissue specificity and regulation of the N-terminal diversity of reticulon 3.". Biochem. J. 385 (Pt 1): 125–34. doi:10.1042/BJ20040458. PMID 15350194. 
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334. 
  • Gan M, Qi Y, Wan Q, et al. (2005). "Mammalian apoptosis-inducing protein, HAP, induces bacterial cell death.". Mol. Biol. Rep. 31 (3): 159–64. PMID 15560370. 
  • Kuang E, Wan Q, Li X, et al. (2005). "ER Ca2+ depletion triggers apoptotic signals for endoplasmic reticulum (ER) overload response induced by overexpressed reticulon 3 (RTN3/HAP).". J. Cell. Physiol. 204 (2): 549–59. doi:10.1002/jcp.20340. PMID 15799019. 
  • Cai Y, Saiyin H, Lin Q, et al. (2005). "Identification of a new RTN3 transcript, RTN3-A1, and its distribution in adult mouse brain.". Brain Res. Mol. Brain Res. 138 (2): 236–43. doi:10.1016/j.molbrainres.2005.04.020. PMID 15946766. 
  • Wakana Y, Koyama S, Nakajima K, et al. (2005). "Reticulon 3 is involved in membrane trafficking between the endoplasmic reticulum and Golgi.". Biochem. Biophys. Res. Commun. 334 (4): 1198–205. doi:10.1016/j.bbrc.2005.07.012. PMID 16054885. 
  • Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network.". Nature 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514. 
  • Otsuki T, Ota T, Nishikawa T, et al. (2007). "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries.". DNA Res. 12 (2): 117–26. doi:10.1093/dnares/12.2.117. PMID 16303743. 
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