Rs6295

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rs6295 is a gene variation—a single nucleotide polymorphism (SNP)— in the HTR1A gene. Is is also refered to as C(-1019)G.

The SNP has been investigated for association with suicide attempts,[1][2] and psychiatric disorders.[3]

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[edit] References

  1. ^ Sylvie Lemonde, Gustavo Turecki, David Bakish, Lisheng Du, Pavel D. Hrdina, Christopher D. Bown, Adolfo Sequeira, Neena Kushwaha, Stephen J. Morris, Ajoy Basak, Xiao-Ming Ou, and Paul R. Albert (September 2003). "Impaired Repression at a 5-Hydroxytryptamine 1A Receptor Gene Polymorphism Associated with Major Depression and Suicide". The Journal of Neuroscience 23 (25): 8788–8799. 
  2. ^ Danuta Wasserman, Thomas Geijer, Marcus Sokolowski, Vsevolod Rozanov and Jerzy Wasserman (2006). "The serotonin 1A receptor C(-1019)G polymorphism in relation to suicide attempt". Behavioral and Brain Functions 2: 14. doi:10.1186/1744-9081-2-14. 
  3. ^ Antonio Drago, Diana De Ronchi and Alessandro Serretti (2007). "5-HT1A gene variants and psychiatric disorders: a review of current literature and selection of SNPs for future studies". Internal Journal of Neuropsychopharmacology. PMID 18047755.