RREB1

From Wikipedia, the free encyclopedia

Ras responsive element binding protein 1

Identifiers

RREB1; FINB; LZ321; RREB-1; Zep-1

External IDs

OMIM: 602209 MGI: 2443664 HomoloGene: 2218

Gene ontology
Molecular Function:	• nucleic acid binding • DNA binding • zinc ion binding • transcription activator activity • metal ion binding
Cellular Component:	• intracellular • nucleus • cytoplasm • nuclear body
Biological Process:	• transcription • regulation of transcription, DNA-dependent • transcription from RNA polymerase II promoter • Ras protein signal transduction • multicellular organismal development

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

n/a

Refseq

NM_001003698 (mRNA)
NP_001003698 (protein)

NM_001013392 (mRNA)
NP_001013410 (protein)

Location

Chr 6: 7.05 - 7.2 Mb

Chr 13: 37.9 - 37.96 Mb

Pubmed search

[1]

[2]

Ras responsive element binding protein 1, also known as RREB1, is a human gene.^[1]

[edit] References

^ Entrez Gene: RREB1 ras responsive element binding protein 1.

[edit] Further reading

Thiagalingam A, De Bustros A, Borges M, et al. (1996). "RREB-1, a novel zinc finger protein, is involved in the differentiation response to Ras in human medullary thyroid carcinomas.". Mol. Cell. Biol. 16 (10): 5335–45. PMID 8816445.
Fujimoto-Nishiyama A, Ishii S, Matsuda S, et al. (1997). "A novel zinc finger protein, Finb, is a transcriptional activator and localized in nuclear bodies.". Gene 195 (2): 267–75. PMID 9305772.
Thiagalingam A, Lengauer C, Baylin SB, Nelkin BD (1998). "RREB1, a ras responsive element binding protein, maps to human chromosome 6p25.". Genomics 45 (3): 630–2. doi:10.1006/geno.1997.5001. PMID 9367691.
Zhang L, Zhao J, Edenberg HJ (1999). "A human Raf-responsive zinc-finger protein that binds to divergent sequences.". Nucleic Acids Res. 27 (14): 2947–56. PMID 10390538.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
Ray SK, Nishitani J, Petry MW, et al. (2003). "Novel transcriptional potentiation of BETA2/NeuroD on the secretin gene promoter by the DNA-binding protein Finb/RREB-1.". Mol. Cell. Biol. 23 (1): 259–71. PMID 12482979.
Zhang S, Qian X, Redman C, et al. (2003). "p16 INK4a gene promoter variation and differential binding of a repressor, the ras-responsive zinc-finger transcription factor, RREB.". Oncogene 22 (15): 2285–95. doi:10.1038/sj.onc.1206257. PMID 12700664.
Shi Y, Sawada J, Sui G, et al. (2003). "Coordinated histone modifications mediated by a CtBP co-repressor complex.". Nature 422 (6933): 735–8. doi:10.1038/nature01550. PMID 12700765.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Date S, Nibu Y, Yanai K, et al. (2005). "Finb, a multiple zinc finger protein, represses transcription of the human angiotensinogen gene.". Int. J. Mol. Med. 13 (5): 637–42. PMID 15067362.
Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins.". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. doi:10.1073/pnas.0404720101. PMID 15302935.