RPS6KC1

From Wikipedia, the free encyclopedia

Ribosomal protein S6 kinase, 52kDa, polypeptide 1

Identifiers

RPS6KC1; RPK118; humS6PKh1

External IDs

Gene ontology
Molecular Function:	• nucleotide binding • protein kinase activity • protein serine/threonine kinase activity • protein binding • ATP binding • transferase activity • phosphoinositide binding
Cellular Component:	• membrane
Biological Process:	• protein amino acid phosphorylation • cell communication • signal transduction

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_012424 (mRNA)
NP_036556 (protein)

NM_178775 (mRNA)
NP_848890 (protein)

Location

Chr 1: 211.29 - 211.51 Mb

Chr 1: 192.45 - 192.61 Mb

Pubmed search

[1]

[2]

Ribosomal protein S6 kinase, 52kDa, polypeptide 1, also known as RPS6KC1, is a human gene.^[1]

[edit] References

^ Entrez Gene: RPS6KC1 ribosomal protein S6 kinase, 52kDa, polypeptide 1.

[edit] Further reading

Zhang H, Yu L, Mao N, et al. (2000). "Cloning, characterization, and chromosome mapping of RPS6KC1, a novel putative member of the ribosome protein S6 kinase family, to chromosome 12q12-q13.1.". Genomics 61 (3): 314–8. doi:10.1006/geno.1999.5963. PMID 10552933.
Hayashi S, Okada T, Igarashi N, et al. (2002). "Identification and characterization of RPK118, a novel sphingosine kinase-1-binding protein.". J. Biol. Chem. 277 (36): 33319–24. doi:10.1074/jbc.M201442200. PMID 12077123.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
Lehner B, Semple JI, Brown SE, et al. (2004). "Analysis of a high-throughput yeast two-hybrid system and its use to predict the function of intracellular proteins encoded within the human MHC class III region.". Genomics 83 (1): 153–67. PMID 14667819.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
Liu L, Yang C, Yuan J, et al. (2005). "RPK118, a PX domain-containing protein, interacts with peroxiredoxin-3 through pseudo-kinase domains.". Mol. Cells 19 (1): 39–45. PMID 15750338.
Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1.". Nature 441 (7091): 315–21. doi:10.1038/nature04727. PMID 16710414.
Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.". Cell 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.