Talk:Rotenone
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Rotenone is within the scope of WikiProject Chemicals, which aims to improve Wikipedia's coverage of chemicals. To participate, help improve this article or visit the project page for details on the project. | ||
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Article Grading: The following comments were left by the quality and importance raters: (edit · refresh) There is a problem with the commentary "The study does not directly suggest that rotenone exposure is responsible for Parkinson's disease in humans ...". The whole point of having animal models for drug studies is that these are convenient and generalizable experimental paradigms for predicting drug actions in humans. So the experimental results in this case DO support the idea that rotenone can cause Parkinson's disease in humans - especially with the other literature that shows a probable mechanism via oxidative damage via microglia. |
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[edit] Needs more Biochemistry
This section needs to detail more information about the exact biochemical mechanism of Rotenone on Complex I. —Preceding unsigned comment added by 70.49.225.80 (talk) 01:16, 4 November 2007 (UTC)
