Roseophilin
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Roseophilin is an antibiotic isolated from Streptomyces griscovirides. The chemical structure can be considered in terms of two components, a macrotricyclic segment and a heterocyclic side-chain. Several syntheses of roseophilin (e.g., those of Trost, Furstner, Salamone) use modified Paal-Knorr conditions.
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