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downloaded from doi:10.1371/journal.pgen.0010070, figure 2 doi:10.1371/journal.pgen.0010070.g002

Inferred Population Structure Based on 1,048 Individuals and 993 Markers, Assuming Correlations among Allele Frequencies across Clusters

Each individual is represented by a thin line partitioned into K colored segments that represent the individual's estimated membership fractions in K clusters. Each plot, produced with DISTRUCT [23], is based on the highest-likelihood run of ten runs: the two runs that were used in further analysis, and the eight runs described under “Cluster Analysis using STRUCTURE.” As in [3], four of ten runs with K = 3 separated a cluster corresponding to East Asia instead of one corresponding to Europe, the Middle East, and Central/South Asia. Two of ten runs with K = 5 separated Surui instead of Oceania. The highest-likelihood run of the ten runs with K = 6, shown in the figure, had a different pattern from the other nine runs (not shown). These other runs, instead of subdividing native Americans into two clusters, subdivided a cluster roughly similar to the Kalash cluster seen in [3], except with a less pronounced separation of the Kalash population. The clusteredness scores for the plots shown with K = 2, 3, 4, 5, and 6 are 0.50, 0.76, 0.84, 0.86, and 0.87, respectively.

From: Rosenberg NA, Mahajan S, Ramachandran S, Zhao C, Pritchard JK, et al. (2005) Clines, Clusters, and the Effect of Study Design on the Inference of Human Population Structure. PLoS Genet 1(6): e70

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