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| RNase E 5' UTR element |
 |
| Type: |
Cis-reg; |
| 2° structure: |
Published; PubMed |
| Seed alignment: |
Griffiths-Jones SR, Moxon SJ |
| Avg length: |
336.6 nucleotides |
| Avg identity: |
76% |
|
RNase E 5' UTR is cis-acting element located in the 5'UTR of ribonuclease (RNase) E messenger RNA (mRNA).
RNase E is a key regulatory enzyme in the pathway of mRNA degradation in Escherichia coli . Its is able to auto-regulate the degradation of its own mRNA in response to changes in RNase E activity. This rne 5' UTR element acts as a sensor of cellular RNase E concentration enabling tight regulation of RNase E concentration and synthesis [1].
[edit] References
- ^ Diwa A, Bricker AL, Jain C, Belasco JG (2000). "An evolutionarily conserved RNA stem-loop functions as a sensor that directs feedback regulation of RNase E gene expression". Genes Dev. 14 (10): 1249–60. PMID 10817759.
[edit] External links
