RHOT2

From Wikipedia, the free encyclopedia

Ras homolog gene family, member T2

Identifiers

RHOT2; ARHT2; C16orf39; MIRO-2; RASL

External IDs

Gene ontology
Molecular Function:	• nucleotide binding • calcium ion binding • GTP binding • hydrolase activity
Cellular Component:	• intracellular • mitochondrion • mitochondrial inner membrane • membrane • integral to membrane • outer membrane • integral to mitochondrial outer membrane
Biological Process:	• apoptosis • small GTPase mediated signal transduction • cell homeostasis • mitochondrion transport along microtubule

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_138769 (mRNA)
NP_620124 (protein)

NM_145999 (mRNA)
NP_666111 (protein)

Location

Chr 16: 0.66 - 0.66 Mb

Chr 17: 25.57 - 25.57 Mb

Pubmed search

[1]

[2]

Ras homolog gene family, member T2, also known as RHOT2, is a human gene.^[1]

[edit] References

^ Entrez Gene: RHOT2 ras homolog gene family, member T2.

[edit] Further reading

Daniels RJ, Peden JF, Lloyd C, et al. (2001). "Sequence, structure and pathology of the fully annotated terminal 2 Mb of the short arm of human chromosome 16.". Hum. Mol. Genet. 10 (4): 339-52. PMID 11157797.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
Fransson A, Ruusala A, Aspenström P (2003). "Atypical Rho GTPases have roles in mitochondrial homeostasis and apoptosis.". J. Biol. Chem. 278 (8): 6495-502. doi:10.1074/jbc.M208609200. PMID 12482879.
Aspenström P, Fransson A, Saras J (2004). "Rho GTPases have diverse effects on the organization of the actin filament system.". Biochem. J. 377 (Pt 2): 327-37. doi:10.1042/BJ20031041. PMID 14521508.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40-5. doi:10.1038/ng1285. PMID 14702039.
Shan Y, Hexige S, Guo Z, et al. (2004). "Cloning and characterization of the mouse Arht2 gene which encodes a putative atypical GTPase.". Cytogenet. Genome Res. 106 (1): 91-7. doi:10.1159/000078568. PMID 15218247.
Colland F, Jacq X, Trouplin V, et al. (2004). "Functional proteomics mapping of a human signaling pathway.". Genome Res. 14 (7): 1324-32. doi:10.1101/gr.2334104. PMID 15231748.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334.
Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network.". Nature 437 (7062): 1173-8. doi:10.1038/nature04209. PMID 16189514.
Fransson S, Ruusala A, Aspenström P (2006). "The atypical Rho GTPases Miro-1 and Miro-2 have essential roles in mitochondrial trafficking.". Biochem. Biophys. Res. Commun. 344 (2): 500-10. doi:10.1016/j.bbrc.2006.03.163. PMID 16630562.