Rhamnulokinase

From Wikipedia, the free encyclopedia

In enzymology, a rhamnulokinase (EC 2.7.1.5) is an enzyme that catalyzes the chemical reaction

ATP + L-rhamnulose ADP + L-rhamnulose 1-phosphate

Thus, the two substrates of this enzyme are ATP and L-rhamnulose, whereas its two products are ADP and L-rhamnulose 1-phosphate.

This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with an alcohol group as acceptor. The systematic name of this enzyme class is ATP:L-rhamnulose 1-phosphotransferase. Other names in common use include RhuK, rhamnulokinase (phosphorylating), L-rhamnulokinase, L-rhamnulose kinase, and rhamnulose kinase. This enzyme participates in pentose and glucuronate interconversions and fructose and mannose metabolism.

Contents 1 Structural studies 2 References 3 External links 3.1 Gene Ontology (GO) codes

[edit] Structural studies

As of late 2007, 4 structures have been solved for this class of enzymes, with PDB accession codes 2CGJ, 2CGK, 2CGL, and 2UYT.

[edit] References

• IUBMB entry for 2.7.1.5
• BRENDA references for 2.7.1.5 (Recommended.)
• PubMed references for 2.7.1.5
• PubMed Central references for 2.7.1.5
• Google Scholar references for 2.7.1.5
• Wilson DM and Ajl S (1957). "Metabolism of L-rhamnose by Escherichia coli. II. The phosphorylation of L-rhamnulose". J. Bacteriol. 73: 415–420. 

[edit] External links

The CAS registry number for this enzyme class is 9030-52-8.

• IUBMB entry for 2.7.1.5

• KEGG entry for 2.7.1.5

• BRENDA entry for 2.7.1.5

• NiceZyme view of 2.7.1.5

• EC2PDB: PDB structures for 2.7.1.5

• PRIAM entry for 2.7.1.5

• PUMA2 entry for 2.7.1.5

• IntEnz: Integrated Enzyme entry for 2.7.1.5

• MetaCyc entry for 2.7.1.5

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0008993: rhamnulokinase

• AMIGO entry for GO code 0008993: rhamnulokinase