Retinol O-fatty-acyltransferase

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In enzymology, a retinol O-fatty-acyltransferase (EC 2.3.1.76) is an enzyme that catalyzes the chemical reaction

acyl-CoA + retinol CoA + retinyl ester

Thus, the two substrates of this enzyme are acyl-CoA and retinol, whereas its two products are CoA and retinyl ester.

This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is acyl-CoA:retinol O-acyltransferase. Other names in common use include retinol acyltransferase, and retinol fatty-acyltransferase. This enzyme participates in retinol metabolism.

[edit] References

• IUBMB entry for 2.3.1.76
• BRENDA references for 2.3.1.76 (Recommended.)
• PubMed references for 2.3.1.76
• PubMed Central references for 2.3.1.76
• Google Scholar references for 2.3.1.76
• Helgerud P, Petersen LB, Norum KR (1983). "Retinol esterification by microsomes from the mucosa of human small intestine. Evidence for acyl-Coenzyme A retinol acyltransferase activity". J. Clin. Invest. 71: 747–53. doi:10.1172/JCI110822. PMID 6826734. 
• Ross AC (1982). "Retinol esterification by rat liver microsomes. Evidence for a fatty acyl coenzyme A: retinol acyltransferase". J. Biol. Chem. 257: 2453–9. PMID 7061433. 

[edit] External links

The CAS registry number for this enzyme class is 81295-48-9.

• IUBMB entry for 2.3.1.76

• KEGG entry for 2.3.1.76

• BRENDA entry for 2.3.1.76

• NiceZyme view of 2.3.1.76

• EC2PDB: PDB structures for 2.3.1.76

• PRIAM entry for 2.3.1.76

• PUMA2 entry for 2.3.1.76

• IntEnz: Integrated Enzyme entry for 2.3.1.76

• MetaCyc entry for 2.3.1.76

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0050252: retinol O-fatty-acyltransferase

• AMIGO entry for GO code 0050252: retinol O-fatty-acyltransferase