RETSAT

From Wikipedia, the free encyclopedia

Retinol saturase (all-trans-retinol 13,14-reductase)

Identifiers

RETSAT; FLJ20296

External IDs

MGI: 1914692 HomoloGene: 41195

Gene ontology
Molecular Function:	• oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen • FAD binding • all-trans-retinol 13,14-reductase activity
Cellular Component:	• nuclear outer membrane • endoplasmic reticulum • endoplasmic reticulum membrane • membrane
Biological Process:	• electron transport • carotenoid biosynthetic process • retinol metabolic process

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_017750 (mRNA)
NP_060220 (protein)

NM_026159 (mRNA)
NP_080435 (protein)

Location

Chr 2: 85.42 - 85.44 Mb

Chr 6: 72.53 - 72.54 Mb

Pubmed search

[1]

[2]

Retinol saturase (all-trans-retinol 13,14-reductase), also known as RETSAT, is a human gene.^[1]

[edit] References

^ Entrez Gene: RETSAT retinol saturase (all-trans-retinol 13,14-reductase).

[edit] Further reading

Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.". Gene 138 (1-2): 171–4. PMID 8125298.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.". Gene 200 (1-2): 149–56. PMID 9373149.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
Clark HF, Gurney AL, Abaya E, et al. (2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMID 12975309.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Moise AR, Kuksa V, Imanishi Y, Palczewski K (2005). "Identification of all-trans-retinol:all-trans-13,14-dihydroretinol saturase.". J. Biol. Chem. 279 (48): 50230–42. doi:10.1074/jbc.M409130200. PMID 15358783.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
Hillier LW, Graves TA, Fulton RS, et al. (2005). "Generation and annotation of the DNA sequences of human chromosomes 2 and 4.". Nature 434 (7034): 724–31. doi:10.1038/nature03466. PMID 15815621.
Otsuki T, Ota T, Nishikawa T, et al. (2007). "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries.". DNA Res. 12 (2): 117–26. doi:10.1093/dnares/12.2.117. PMID 16303743.