RBM6

From Wikipedia, the free encyclopedia

RNA binding motif protein 6

Identifiers

RBM6; DEF3; 3G2; DEF-3; DKFZp686B0877; FLJ36517; HLC-11; NY-LU-12; g16

External IDs

OMIM: 606886 MGI: 1338037 HomoloGene: 31336

Gene ontology
Molecular Function:	• nucleic acid binding • DNA binding • RNA binding • zinc ion binding
Cellular Component:	• intracellular • nucleus
Biological Process:	• RNA processing

Orthologs

Human

Mouse

n/a

Refseq

NM_005777 (mRNA)
NP_005768 (protein)

NM_011251 (mRNA)
NP_035381 (protein)

Location

Chr 3: 49.95 - 50.09 Mb

Chr 9: 107.63 - 107.73 Mb

Pubmed search

[1]

[2]

RNA binding motif protein 6, also known as RBM6, is a human gene.^[1]

[edit] References

^ Entrez Gene: RBM6 RNA binding motif protein 6.

[edit] Further reading

Güre AO, Altorki NK, Stockert E, et al. (1998). "Human lung cancer antigens recognized by autologous antibodies: definition of a novel cDNA derived from the tumor suppressor gene locus on chromosome 3p21.3.". Cancer Res. 58 (5): 1034–41. PMID 9500467.
Timmer T, Terpstra P, van den Berg A, et al. (1999). "A comparison of genomic structures and expression patterns of two closely related flanking genes in a critical lung cancer region at 3p21.3.". Eur. J. Hum. Genet. 7 (4): 478–86. doi:10.1038/sj.ejhg.5200334. PMID 10352938.
Drabkin HA, West JD, Hotfilder M, et al. (1999). "DEF-3(g16/NY-LU-12), an RNA binding protein from the 3p21.3 homozygous deletion region in SCLC.". Oncogene 18 (16): 2589–97. doi:10.1038/sj.onc.1202601. PMID 10353602.
Timmer T, Terpstra P, van den Berg A, et al. (1999). "An evolutionary rearrangement of the Xp11.3-11.23 region in 3p21.3, a region frequently deleted in a variety of cancers.". Genomics 60 (2): 238–40. doi:10.1006/geno.1999.5878. PMID 10486216.
Lerman MI, Minna JD (2000). "The 630-kb lung cancer homozygous deletion region on human chromosome 3p21.3: identification and evaluation of the resident candidate tumor suppressor genes. The International Lung Cancer Chromosome 3p21.3 Tumor Suppressor Gene Consortium.". Cancer Res. 60 (21): 6116–33. PMID 11085536.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins.". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. doi:10.1073/pnas.0404720101. PMID 15302935.
Beausoleil SA, Villén J, Gerber SA, et al. (2006). "A probability-based approach for high-throughput protein phosphorylation analysis and site localization.". Nat. Biotechnol. 24 (10): 1285–92. doi:10.1038/nbt1240. PMID 16964243.
Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.". Cell 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.
Gu TL, Mercher T, Tyner JW, et al. (2007). "A novel fusion of RBM6 to CSF1R in acute megakaryoblastic leukemia.". Blood 110 (1): 323–33. doi:10.1182/blood-2006-10-052282. PMID 17360941.
Wang K, Ubriaco G, Sutherland LC. "RBM6-RBM5 transcription-induced chimeras are differentially expressed in tumours.". BMC Genomics 8: 348. doi:10.1186/1471-2164-8-348. PMID 17908320.