RBM3

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RNA binding motif (RNP1, RRM) protein 3
Identifiers
Symbol(s) RBM3; IS1-RNPL; RNPL
External IDs OMIM: 300027 MGI: 1099460 HomoloGene: 31404
RNA expression pattern

More reference expression data
Orthologs
Human Mouse
Entrez 5935 19652
Ensembl ENSG00000102317 ENSMUSG00000031167
Uniprot P98179 Q545K5
Refseq NM_001017430 (mRNA)
NP_001017430 (protein)		 NM_016809 (mRNA)
NP_058089 (protein)
Location Chr X: 48.32 - 48.32 Mb Chr X: 7.3 - 7.3 Mb
Pubmed search [1] [2]

RNA binding motif (RNP1, RRM) protein 3, also known as RBM3, is a human gene.[1]

This gene is a member of the glycine-rich RNA-binding protein family and encodes a protein with one RNA recognition motif (RRM) domain. Expression of this gene is induced by cold shock and low oxygen tension. A pseudogene exists on chromosome 1. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.[1]

[edit] References

  1. ^ a b Entrez Gene: RBM3 RNA binding motif (RNP1, RRM) protein 3.

[edit] Further reading

  • Derry JM, Kerns JA, Francke U (1996). "RBM3, a novel human gene in Xp11.23 with a putative RNA-binding domain.". Hum. Mol. Genet. 4 (12): 2307-11. PMID 8634703. 
  • Danno S, Nishiyama H, Higashitsuji H, et al. (1997). "Increased transcript level of RBM3, a member of the glycine-rich RNA-binding protein family, in human cells in response to cold stress.". Biochem. Biophys. Res. Commun. 236 (3): 804-7. doi:10.1006/bbrc.1997.7059. PMID 9245737. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Chappell SA, Mauro VP (2003). "The internal ribosome entry site (IRES) contained within the RNA-binding motif protein 3 (Rbm3) mRNA is composed of functionally distinct elements.". J. Biol. Chem. 278 (36): 33793-800. doi:10.1074/jbc.M303495200. PMID 12824175. 
  • Wellmann S, Bührer C, Moderegger E, et al. (2004). "Oxygen-regulated expression of the RNA-binding proteins RBM3 and CIRP by a HIF-1-independent mechanism.". J. Cell. Sci. 117 (Pt 9): 1785-94. doi:10.1242/jcs.01026. PMID 15075239. 
  • Brill LM, Salomon AR, Ficarro SB, et al. (2004). "Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using immobilized metal affinity chromatography and tandem mass spectrometry.". Anal. Chem. 76 (10): 2763-72. doi:10.1021/ac035352d. PMID 15144186. 
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334. 
  • Dellis S, Strickland KC, McCrary WJ, et al. (2005). "Protein interactions among the vaccinia virus late transcription factors.". Virology 329 (2): 328-36. doi:10.1016/j.virol.2004.08.017. PMID 15518812. 
  • Andersen JS, Lam YW, Leung AK, et al. (2005). "Nucleolar proteome dynamics.". Nature 433 (7021): 77-83. doi:10.1038/nature03207. PMID 15635413. 
  • Ross MT, Grafham DV, Coffey AJ, et al. (2005). "The DNA sequence of the human X chromosome.". Nature 434 (7031): 325-37. doi:10.1038/nature03440. PMID 15772651. 
  • Ong SE, Mittler G, Mann M (2005). "Identifying and quantifying in vivo methylation sites by heavy methyl SILAC.". Nat. Methods 1 (2): 119-26. doi:10.1038/nmeth715. PMID 15782174. 
  • Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network.". Nature 437 (7062): 1173-8. doi:10.1038/nature04209. PMID 16189514. 
  • Martínez-Arribas F, Agudo D, Pollán M, et al. (2006). "Positive correlation between the expression of X-chromosome RBM genes (RBMX, RBM3, RBM10) and the proapoptotic Bax gene in human breast cancer.". J. Cell. Biochem. 97 (6): 1275-82. doi:10.1002/jcb.20725. PMID 16552754. 
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