RAPGEF6

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Rap guanine nucleotide exchange factor (GEF) 6
PDB rendering based on 2d93.
Available structures: 2d93
Identifiers
Symbol(s) RAPGEF6; DKFZp667N084; DKFZp686I15116; KIA001LB; PDZ-GEF2; PDZGEF2; RA-GEF-2
External IDs OMIM: 610499 MGI: 2384761 HomoloGene: 22968
Orthologs
Human Mouse
Entrez 51735 192786
Ensembl n/a ENSMUSG00000037533
Refseq NM_016340 (mRNA)
NP_057424 (protein)		 NM_175258 (mRNA)
NP_780467 (protein)
Location n/a Chr 11: 54.37 - 54.54 Mb
Pubmed search [1] [2]

Rap guanine nucleotide exchange factor (GEF) 6, also known as RAPGEF6, is a human gene.[1]


[edit] References

  1. ^ Entrez Gene: RAPGEF6 Rap guanine nucleotide exchange factor (GEF) 6.

[edit] Further reading

  • Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.". Cell 127 (3): 635-48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. 
  • Chen X, Wang X, Hossain S, et al. (2006). "Haplotypes spanning SPEC2, PDZ-GEF2 and ACSL6 genes are associated with schizophrenia.". Hum. Mol. Genet. 15 (22): 3329-42. doi:10.1093/hmg/ddl409. PMID 17030554. 
  • Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins.". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130-5. doi:10.1073/pnas.0404720101. PMID 15302935. 
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40-5. doi:10.1038/ng1285. PMID 14702039. 
  • Kuiperij HB, de Rooij J, Rehmann H, et al. (2003). "Characterisation of PDZ-GEFs, a family of guanine nucleotide exchange factors specific for Rap1 and Rap2.". Biochim. Biophys. Acta 1593 (2-3): 141-9. PMID 12581858. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Kozlov G, Banville D, Gehring K, Ekiel I (2002). "Solution structure of the PDZ2 domain from cytosolic human phosphatase hPTP1E complexed with a peptide reveals contribution of the beta2-beta3 loop to PDZ domain-ligand interactions.". J. Mol. Biol. 320 (4): 813-20. PMID 12095257. 
  • Gao X, Satoh T, Liao Y, et al. (2001). "Identification and characterization of RA-GEF-2, a Rap guanine nucleotide exchange factor that serves as a downstream target of M-Ras.". J. Biol. Chem. 276 (45): 42219-25. doi:10.1074/jbc.M105760200. PMID 11524421. 
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