RAI2

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Retinoic acid induced 2
Identifiers
Symbol(s) RAI2;
External IDs OMIM: 300217 MGI: 1344378 HomoloGene: 11034
RNA expression pattern

More reference expression data
Orthologs
Human Mouse
Entrez 10742 24004
Ensembl ENSG00000131831 ENSMUSG00000043518
Uniprot Q9Y5P3 Q3UPL8
Refseq NM_021785 (mRNA)
NP_068557 (protein)		 XM_622964 (mRNA)
XP_622964 (protein)
Location Chr X: 17.73 - 17.79 Mb Chr X: 157.06 - 157.12 Mb
Pubmed search [1] [2]

Retinoic acid induced 2, also known as RAI2, is a human gene.[1]

Retinoic acid plays a critical role in development, cellular growth, and differentiation. The specific function of this intronless, retinoic acid-induced gene has not yet been determined; however, it has been suggested to play a role in development. Localization of this gene designates it to be a candidate for diseases such as Nance-Horan syndrome, sensorineural deafness, non-specific X-linked mental retardation, oral-facial-digital syndrome, and Fried syndrome.[1]

[edit] References

  1. ^ a b Entrez Gene: RAI2 retinoic acid induced 2.

[edit] Further reading

  • Lim J, Hao T, Shaw C, et al. (2006). "A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.". Cell 125 (4): 801-14. doi:10.1016/j.cell.2006.03.032. PMID 16713569. 
  • Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network.". Nature 437 (7062): 1173-8. doi:10.1038/nature04209. PMID 16189514. 
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334. 
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40-5. doi:10.1038/ng1285. PMID 14702039. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Walpole SM, Ronce N, Grayson C, et al. (1999). "Exclusion of RAI2 as the causative gene for Nance-Horan syndrome.". Hum. Genet. 104 (5): 410-1. PMID 10394933. 
  • Walpole SM, Hiriyana KT, Nicolaou A, et al. (1999). "Identification and characterization of the human homologue (RAI2) of a mouse retinoic acid-induced gene in Xp22.". Genomics 55 (3): 275-83. doi:10.1006/geno.1998.5667. PMID 10049581. 
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