RAB6B

From Wikipedia, the free encyclopedia

RAB6B, member RAS oncogene family

PDB rendering based on 1yzq.

Available structures: 1yzq, 2fe4, 2ffq, 2gil

Identifiers

Symbol(s)

RAB6B;

External IDs

MGI: 107283 HomoloGene: 39749

Gene ontology
Molecular Function:	• nucleotide binding • GTPase activity • GTP binding
Cellular Component:	• Golgi apparatus
Biological Process:	• ER to Golgi vesicle-mediated transport • retrograde vesicle-mediated transport, Golgi to ER • small GTPase mediated signal transduction • protein transport

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_016577 (mRNA)
NP_057661 (protein)

NM_173781 (mRNA)
NP_776142 (protein)

Location

Chr 3: 135.03 - 135.1 Mb

Chr 9: 102.97 - 103.04 Mb

Pubmed search

[1]

[2]

RAB6B, member RAS oncogene family, also known as RAB6B, is a human gene.^[1]

[edit] References

^ Entrez Gene: RAB6B RAB6B, member RAS oncogene family.

[edit] Further reading

Chen D, Guo J, Gahl WA (1997). "RAB GTPases expressed in human melanoma cells.". Biochim. Biophys. Acta 1355 (1): 1–6. PMID 9030196.
Opdam FJ, Echard A, Croes HJ, et al. (2000). "The small GTPase Rab6B, a novel Rab6 subfamily member, is cell-type specifically expressed and localised to the Golgi apparatus.". J. Cell. Sci. 113 ( Pt 15): 2725–35. PMID 10893188.
Monier S, Jollivet F, Janoueix-Lerosey I, et al. (2002). "Characterization of novel Rab6-interacting proteins involved in endosome-to-TGN transport.". Traffic 3 (4): 289–97. PMID 11929610.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network.". Nature 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.
Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes.". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMID 16344560.
Garcia-Saez I, Tcherniuk S, Kozielski F (2006). "The structure of human neuronal Rab6B in the active and inactive form.". Acta Crystallogr. D Biol. Crystallogr. 62 (Pt 7): 725–33. doi:10.1107/S0907444906015319. PMID 16790928.
Wanschers BF, van de Vorstenbosch R, Schlager MA, et al. (2007). "A role for the Rab6B Bicaudal-D1 interaction in retrograde transport in neuronal cells.". Exp. Cell Res. 313 (16): 3408–20. doi:10.1016/j.yexcr.2007.05.032. PMID 17707369.