RAB4A

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RAB4A, member RAS oncogene family
PDB rendering based on 1yu9.
Available structures: 1yu9, 1z0k, 2bmd, 2bme
Identifiers
Symbol(s) RAB4A; RAB4
External IDs OMIM: 179511 MGI: 105069 HomoloGene: 55834
Orthologs
Human Mouse
Entrez 5867 19341
Ensembl n/a ENSMUSG00000019478
Uniprot n/a Q3TSQ6
Refseq NM_004578 (mRNA)
NP_004569 (protein)		 NM_009003 (mRNA)
NP_033029 (protein)
Location n/a Chr 8: 126.69 - 126.72 Mb
Pubmed search [1] [2]

RAB4A, member RAS oncogene family, also known as RAB4A, is a human gene.[1]


[edit] References

  1. ^ Entrez Gene: RAB4A RAB4A, member RAS oncogene family.

[edit] Further reading

  • Stibbs HH, Seed JR (1975). "Short-term metabolism of (14-C) tryptophan in rats infected with Trypanosoma brucei gambiense.". J. Infect. Dis. 131 (4): 459–62. PMID 1117200. 
  • van der Sluijs P, Hull M, Huber LA, et al. (1992). "Reversible phosphorylation--dephosphorylation determines the localization of rab4 during the cell cycle.". EMBO J. 11 (12): 4379–89. PMID 1425574. 
  • Bailly E, McCaffrey M, Touchot N, et al. (1991). "Phosphorylation of two small GTP-binding proteins of the Rab family by p34cdc2.". Nature 350 (6320): 715–8. doi:10.1038/350715a0. PMID 1902553. 
  • Rousseau-Merck MF, Zahraoui A, Touchot N, et al. (1991). "Chromosome assignment of four RAS-related RAB genes.". Hum. Genet. 86 (4): 350–4. PMID 1999336. 
  • Zahraoui A, Touchot N, Chardin P, Tavitian A (1989). "The human Rab genes encode a family of GTP-binding proteins related to yeast YPT1 and SEC4 products involved in secretion.". J. Biol. Chem. 264 (21): 12394–401. PMID 2501306. 
  • Cormont M, Tanti JF, Zahraoui A, et al. (1994). "Rab4 is phosphorylated by the insulin-activated extracellular-signal-regulated kinase ERK1.". Eur. J. Biochem. 219 (3): 1081–5. PMID 8112321. 
  • Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.". Gene 138 (1-2): 171–4. PMID 8125298. 
  • Karniguian A, Zahraoui A, Tavitian A (1993). "Identification of small GTP-binding rab proteins in human platelets: thrombin-induced phosphorylation of rab3B, rab6, and rab8 proteins.". Proc. Natl. Acad. Sci. U.S.A. 90 (16): 7647–51. PMID 8356066. 
  • Valentijn JA, LaCivita DQ, Gumkowski FD, Jamieson JD (1997). "Rab4 associates with the actin terminal web in developing rat pancreatic acinar cells.". Eur. J. Cell Biol. 72 (1): 1–8. PMID 9013719. 
  • Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.". Gene 200 (1-2): 149–56. PMID 9373149. 
  • Vitale G, Rybin V, Christoforidis S, et al. (1998). "Distinct Rab-binding domains mediate the interaction of Rabaptin-5 with GTP-bound Rab4 and Rab5.". EMBO J. 17 (7): 1941–51. doi:10.1093/emboj/17.7.1941. PMID 9524117. 
  • Bucci C, Chiariello M, Lattero D, et al. (1999). "Interaction cloning and characterization of the cDNA encoding the human prenylated rab acceptor (PRA1).". Biochem. Biophys. Res. Commun. 258 (3): 657–62. doi:10.1006/bbrc.1999.0651. PMID 10329441. 
  • Shisheva A, Chinni SR, DeMarco C (1999). "General role of GDP dissociation inhibitor 2 in membrane release of Rab proteins: modulations of its functional interactions by in vitro and in vivo structural modifications.". Biochemistry 38 (36): 11711–21. PMID 10512627. 
  • Nagelkerken B, Van Anken E, Van Raak M, et al. (2000). "Rabaptin4, a novel effector of the small GTPase rab4a, is recruited to perinuclear recycling vesicles.". Biochem. J. 346 Pt 3: 593–601. PMID 10698684. 
  • Gerez L, Mohrmann K, van Raak M, et al. (2000). "Accumulation of rab4GTP in the cytoplasm and association with the peptidyl-prolyl isomerase pin1 during mitosis.". Mol. Biol. Cell 11 (7): 2201–11. PMID 10888662. 
  • Li L, Omata W, Kojima I, Shibata H (2001). "Direct interaction of Rab4 with syntaxin 4.". J. Biol. Chem. 276 (7): 5265–73. doi:10.1074/jbc.M003883200. PMID 11063739. 
  • Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination.". Genome Res. 10 (11): 1788–95. PMID 11076863. 
  • Cormont M, Mari M, Galmiche A, et al. (2001). "A FYVE-finger-containing protein, Rabip4, is a Rab4 effector involved in early endosomal traffic.". Proc. Natl. Acad. Sci. U.S.A. 98 (4): 1637–42. doi:10.1073/pnas.031586998. PMID 11172003. 
  • Bielli A, Thörnqvist PO, Hendrick AG, et al. (2001). "The small GTPase Rab4A interacts with the central region of cytoplasmic dynein light intermediate chain-1.". Biochem. Biophys. Res. Commun. 281 (5): 1141–53. doi:10.1006/bbrc.2001.4468. PMID 11243854. 
  • Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing.". EMBO Rep. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMID 11256614. 
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