RAB18

From Wikipedia, the free encyclopedia

RAB18, member RAS oncogene family

PDB rendering based on 1x3s.

Available structures: 1x3s

Identifiers

Symbol(s)

RAB18; RAB18LI1

External IDs

OMIM: 602207 MGI: 102790 HomoloGene: 40765

Gene ontology
Molecular Function:	• nucleotide binding • GTPase activity • ATP binding • GTP binding • transcription factor binding
Cellular Component:	• cellular_component • intracellular • membrane
Biological Process:	• regulation of transcription, DNA-dependent • endocytosis • small GTPase mediated signal transduction • protein transport

Orthologs

Human

Mouse

Refseq

NM_021252 (mRNA)
NP_067075 (protein)

NM_011225 (mRNA)
NP_035355 (protein)

Location

Chr 10: 27.83 - 27.87 Mb

Chr 18: 6.77 - 6.79 Mb

Pubmed search

[1]

[2]

RAB18, member RAS oncogene family, also known as RAB18, is a human gene.^[1]

[edit] References

^ Entrez Gene: RAB18 RAB18, member RAS oncogene family.

[edit] Further reading

Adams MD, Kerlavage AR, Fleischmann RD, et al. (1995). "Initial assessment of human gene diversity and expression patterns based upon 83 million nucleotides of cDNA sequence.". Nature 377 (6547 Suppl): 3–174. PMID 7566098.
Lütcke A, Parton RG, Murphy C, et al. (1995). "Cloning and subcellular localization of novel rab proteins reveals polarized and cell type-specific expression.". J. Cell. Sci. 107 ( Pt 12): 3437–48. PMID 7706395.
Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.". Gene 138 (1-2): 171–4. PMID 8125298.
Hillier LD, Lennon G, Becker M, et al. (1997). "Generation and analysis of 280,000 human expressed sequence tags.". Genome Res. 6 (9): 807–28. PMID 8889549.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.". Gene 200 (1-2): 149–56. PMID 9373149.
Schäfer U, Seibold S, Schneider A, Neugebauer E (2000). "Isolation and characterisation of the human rab18 gene after stimulation of endothelial cells with histamine.". FEBS Lett. 466 (1): 148–54. PMID 10648831.
Hu RM, Han ZG, Song HD, et al. (2000). "Gene expression profiling in the human hypothalamus-pituitary-adrenal axis and full-length cDNA cloning.". Proc. Natl. Acad. Sci. U.S.A. 97 (17): 9543–8. doi:10.1073/pnas.160270997. PMID 10931946.
Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination.". Genome Res. 10 (11): 1788–95. PMID 11076863.
Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs.". Genome Res. 11 (3): 422–35. doi:10.1101/gr.154701. PMID 11230166.
Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing.". EMBO Rep. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMID 11256614.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
Behrends U, Schneider I, Rössler S, et al. (2003). "Novel tumor antigens identified by autologous antibody screening of childhood medulloblastoma cDNA libraries.". Int. J. Cancer 106 (2): 244–51. doi:10.1002/ijc.11208. PMID 12800201.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Deloukas P, Earthrowl ME, Grafham DV, et al. (2004). "The DNA sequence and comparative analysis of human chromosome 10.". Nature 429 (6990): 375–81. doi:10.1038/nature02462. PMID 15164054.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline.". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMID 15489336.
Ozeki S, Cheng J, Tauchi-Sato K, et al. (2005). "Rab18 localizes to lipid droplets and induces their close apposition to the endoplasmic reticulum-derived membrane.". J. Cell. Sci. 118 (Pt 12): 2601–11. doi:10.1242/jcs.02401. PMID 15914536.
Dou T, Ji C, Gu S, et al. (2006). "Cloning and characterization of a novel splice variant of human Rab18 gene (RAB18).". DNA Seq. 16 (3): 230–4. doi:10.1080/10425170500061681. PMID 16147880.
Martin S, Driessen K, Nixon SJ, et al. (2006). "Regulated localization of Rab18 to lipid droplets: effects of lipolytic stimulation and inhibition of lipid droplet catabolism.". J. Biol. Chem. 280 (51): 42325–35. doi:10.1074/jbc.M506651200. PMID 16207721.
Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006.". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMID 16381901.