Quinoline-4-carboxylate 2-oxidoreductase

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In enzymology, a quinoline-4-carboxylate 2-oxidoreductase (EC 1.3.99.19) is an enzyme that catalyzes the chemical reaction

quinoline-4-carboxylate + acceptor + H₂O $\rightleftharpoons$ 2-oxo-1,2-dihydroquinoline-4-carboxylate + reduced acceptor

The 3 substrates of this enzyme are quinoline-4-carboxylate, acceptor, and H₂O, whereas its two products are 2-oxo-1,2-dihydroquinoline-4-carboxylate and reduced acceptor.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with other acceptors. The systematic name of this enzyme class is quinoline-4-carboxylate:acceptor 2-oxidoreductase (hydroxylating). Other names in common use include quinaldic acid 4-oxidoreductase, and quinoline-4-carboxylate:acceptor 2-oxidoreductase (hydroxylating).

[edit] References

IUBMB entry for 1.3.99.19
BRENDA references for 1.3.99.19 (Recommended.)
PubMed references for 1.3.99.19
PubMed Central references for 1.3.99.19
Google Scholar references for 1.3.99.19
Bauer G, Lingens F (1992). "Microbial metabolism of quinoline and related compounds. XV Quinoline-4-carboxylic acid oxidoreductase from Agrobacterium spec.1B: a molybdenum-containing enzyme". Biol. Chem. Hoppe. Seyler. 373: 699–705. PMID 1418685.