Quinaldine
From Wikipedia, the free encyclopedia
| Quinaldine | |
|---|---|
 |
|
| IUPAC name | 2-Methylquinoline |
| Other names | Quinaldine, 2-methylchinolin, α-methylquinoline, chinaldine, khinaldin |
| Identifiers | |
| CAS number | [91-63-4] |
| PubChem | |
| EINECS number | |
| SMILES | Cc1nc2ccccc2cc1 |
| InChI | 1/C10H9N/c1-8-6-7-9-4-2-3-5-10(9)11-8/h2-7H,1H3 |
| Properties | |
| Molecular formula | C10H9N |
| Molar mass | 143.19 g/mol |
| Appearance | Clear to yellow oily liquid |
| Density | 1.058 g/cm3 |
| Melting point |
-2 °C |
| Boiling point |
248 °C |
| Solubility in water | Insoluble |
| Hazards | |
| Main hazards | Harmful (Xn), Corrosive (C) |
| NFPA 704 |
 2
2
0
|
| R-phrases | R21/22 R34 |
| Flash point | 79 °C |
| Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) Infobox disclaimer and references |
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Quinaldine or 2-metylquinoline is a simple derivative of a heterocyclic compound quinoline.
Quinaldine has critical point at 787 K and 4.9 MPa and its refractive index is 1.8116.
It can be prepared from aniline and paraldehyde via Skraup synthesis or from aniline and crotonaldehyde via Doebner-von Miller Variation of the Skraup Reaction[1] or extracted from coal tar.
[edit] Uses
Quinaldine is used in anti-malaria drugss, in manufacturing dyes, food colorants (e.g. Quinoline Yellow WS), pharmaceuticals, pH indicators.
Quinaldine sulphate is an anaesthetic used in fish transportation.[2]
[edit] References
- ^ Classical methods of synthesizing quinolines
- ^ Blasiola G. C. Jr. (1977). "Quinaldine sulphate, a new anaesthetic formulation for tropical marine fishes". Journal of Fish Biology 10 (2): 113–119(7). doi:.
[edit] External links
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