Pyridine N-methyltransferase

From Wikipedia, the free encyclopedia

In enzymology, a pyridine N-methyltransferase (EC 2.1.1.87) is an enzyme that catalyzes the chemical reaction

S-adenosyl-L-methionine + pyridine S-adenosyl-L-homocysteine + N-methylpyridinium

Thus, the two substrates of this enzyme are S-adenosyl methionine and pyridine, whereas its two products are S-adenosylhomocysteine and N-methylpyridinium.

This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is S-adenosyl-L-methionine:pyridine N-methyltransferase. This enzyme is also called pyridine methyltransferase.

[edit] References

• IUBMB entry for 2.1.1.87
• BRENDA references for 2.1.1.87 (Recommended.)
• PubMed references for 2.1.1.87
• PubMed Central references for 2.1.1.87
• Google Scholar references for 2.1.1.87
• Damani LA, Shaker MS, Crooks PA, Godin CS, Nwosu C (1986). "N-methylation and quaternization of pyridine in vitro by rabbit lung, liver and kidney N-methyltransferases: an S-adenosyl-L-methionine-dependent reaction". Xenobiotica. 16: 645–50. PMID 3751119. 

[edit] External links

The CAS registry number for this enzyme class is 104327-10-8.

• IUBMB entry for 2.1.1.87

• KEGG entry for 2.1.1.87

• BRENDA entry for 2.1.1.87

• NiceZyme view of 2.1.1.87

• EC2PDB: PDB structures for 2.1.1.87

• PRIAM entry for 2.1.1.87

• PUMA2 entry for 2.1.1.87

• IntEnz: Integrated Enzyme entry for 2.1.1.87

• MetaCyc entry for 2.1.1.87

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0030760: pyridine N-methyltransferase

• AMIGO entry for GO code 0030760: pyridine N-methyltransferase