PUM2

From Wikipedia, the free encyclopedia


Pumilio homolog 2 (Drosophila)
PDB rendering based on 1ib2.
Available structures: 1ib2, 1m8w, 1m8x, 1m8y, 1m8z
Identifiers
Symbol(s) PUM2; FLJ36528; KIAA0235; MGC138251; MGC138253; PUMH2; PUML2
External IDs OMIM: 607205 MGI: 1931751 HomoloGene: 69183
RNA expression pattern

More reference expression data
Orthologs
Human Mouse
Entrez 23369 80913
Ensembl ENSG00000055917 ENSMUSG00000020594
Uniprot Q8TB72 Q3TTH9
Refseq NM_015317 (mRNA)
NP_056132 (protein)		 XM_978653 (mRNA)
XP_983747 (protein)
Location Chr 2: 20.31 - 20.41 Mb Chr 12: 8.7 - 8.78 Mb
Pubmed search [1] [2]

Pumilio homolog 2 (Drosophila), also known as PUM2, is a human gene.[1]


[edit] References

  1. ^ Entrez Gene: PUM2 pumilio homolog 2 (Drosophila).

[edit] Further reading

  • Nakajima D, Okazaki N, Yamakawa H, et al. (2003). "Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.". DNA Res. 9 (3): 99–106. PMID 12168954. 
  • Spik A, Oczkowski S, Olszak A, et al. (2006). "Candidate mRNAs interacting with fertility protein PUMILIO2 in the human germ line.". Reproductive biology 6 Suppl 1: 37–42. PMID 16967088. 
  • Nagase T, Seki N, Ishikawa K, et al. (1997). "Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain.". DNA Res. 3 (5): 321–9, 341–54. PMID 9039502. 
  • Nakayama M, Kikuno R, Ohara O (2003). "Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.". Genome Res. 12 (11): 1773–84. doi:10.1101/gr.406902. PMID 12421765. 
  • Spassov DS, Jurecic R (2003). "Cloning and comparative sequence analysis of PUM1 and PUM2 genes, human members of the Pumilio family of RNA-binding proteins.". Gene 299 (1-2): 195–204. PMID 12459267. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Moore FL, Jaruzelska J, Fox MS, et al. (2003). "Human Pumilio-2 is expressed in embryonic stem cells and germ cells and interacts with DAZ (Deleted in AZoospermia) and DAZ-like proteins.". Proc. Natl. Acad. Sci. U.S.A. 100 (2): 538–43. doi:10.1073/pnas.0234478100. PMID 12511597. 
  • Jaruzelska J, Kotecki M, Kusz K, et al. (2004). "Conservation of a Pumilio-Nanos complex from Drosophila germ plasm to human germ cells.". Dev. Genes Evol. 213 (3): 120–6. doi:10.1007/s00427-003-0303-2. PMID 12690449. 
  • Dazard JE, Gal H, Amariglio N, et al. (2003). "Genome-wide comparison of human keratinocyte and squamous cell carcinoma responses to UVB irradiation: implications for skin and epithelial cancer.". Oncogene 22 (19): 2993–3006. doi:10.1038/sj.onc.1206537. PMID 12771951. 
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039. 
  • Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins.". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. doi:10.1073/pnas.0404720101. PMID 15302935. 
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334. 
  • Fox M, Urano J, Reijo Pera RA (2005). "Identification and characterization of RNA sequences to which human PUMILIO-2 (PUM2) and deleted in Azoospermia-like (DAZL) bind.". Genomics 85 (1): 92–105. doi:10.1016/j.ygeno.2004.10.003. PMID 15607425. 
  • Scott RE, White-Grindley E, Ruley HE, et al. (2005). "P2P-R expression is genetically coregulated with components of the translation machinery and with PUM2, a translational repressor that associates with the P2P-R mRNA.". J. Cell. Physiol. 204 (1): 99–105. doi:10.1002/jcp.20263. PMID 15617101. 
  • Hillier LW, Graves TA, Fulton RS, et al. (2005). "Generation and annotation of the DNA sequences of human chromosomes 2 and 4.". Nature 434 (7034): 724–31. doi:10.1038/nature03466. PMID 15815621. 
  • Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.". Cell 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. 
  • Kusz K, Ginter-Matuszewska B, Ziolkowska K, et al. (2007). "Polymorphisms of the human PUMILIO2 gene and male sterility.". Mol. Reprod. Dev. 74 (6): 795–9. doi:10.1002/mrd.20683. PMID 17154300. 
 This article on a gene on chromosome 2 is a stub. You can help Wikipedia by expanding it.