PTENP1

From Wikipedia, the free encyclopedia

Phosphatase and tensin homolog (mutated in multiple advanced cancers 1), pseudogene 1

Identifiers

PTENP1; PTEN2; PTEN-rs; PTH2; psiPTEN

Gene ontology
Molecular Function:	• protein tyrosine/serine/threonine phosphatase activity • hydrolase activity
Biological Process:	• protein amino acid dephosphorylation

Orthologs

Human

Mouse

Entrez

11191

n/a

Pubmed search

[1]

n/a

Phosphatase and tensin homolog (mutated in multiple advanced cancers 1), pseudogene 1, also known as PTENP1, is a human gene.^[1]

[edit] References

^ Entrez Gene: PTENP1 phosphatase and tensin homolog (mutated in multiple advanced cancers 1), pseudogene 1.

[edit] Further reading

Kong D, Suzuki A, Zou TT, et al. (1997). "PTEN1 is frequently mutated in primary endometrial carcinomas.". Nat. Genet. 17 (2): 143-4. doi:10.1038/ng1097-143. PMID 9326929.
Teng DH, Hu R, Lin H, et al. (1998). "MMAC1/PTEN mutations in primary tumor specimens and tumor cell lines.". Cancer Res. 57 (23): 5221-5. PMID 9393738.
Sakurada A, Suzuki A, Sato M, et al. (1998). "Infrequent genetic alterations of the PTEN/MMAC1 gene in Japanese patients with primary cancers of the breast, lung, pancreas, kidney, and ovary.". Jpn. J. Cancer Res. 88 (11): 1025-8. PMID 9439675.
Kim SK, Su LK, Oh Y, et al. (1998). "Alterations of PTEN/MMAC1, a candidate tumor suppressor gene, and its homologue, PTH2, in small cell lung cancer cell lines.". Oncogene 16 (1): 89-93. doi:10.1038/sj.onc.1201512. PMID 9467947.
Dahia PL, FitzGerald MG, Zhang X, et al. (1998). "A highly conserved processed PTEN pseudogene is located on chromosome band 9p21.". Oncogene 16 (18): 2403-6. doi:10.1038/sj.onc.1201762. PMID 9620558.
Forgacs E, Biesterveld EJ, Sekido Y, et al. (1998). "Mutation analysis of the PTEN/MMAC1 gene in lung cancer.". Oncogene 17 (12): 1557-65. doi:10.1038/sj.onc.1202070. PMID 9794233.
Fujii GH, Morimoto AM, Berson AE, Bolen JB (1999). "Transcriptional analysis of the PTEN/MMAC1 pseudogene, psiPTEN.". Oncogene 18 (9): 1765-9. doi:10.1038/sj.onc.1202492. PMID 10208437.
Trojan J, Plotz G, Brieger A, et al. (2002). "Activation of a cryptic splice site of PTEN and loss of heterozygosity in benign skin lesions in Cowden disease.". J. Invest. Dermatol. 117 (6): 1650-3. doi:10.1046/j.0022-202x.2001.01954.x. PMID 11886535.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.