Psychosine sulfotransferase

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In enzymology, a psychosine sulfotransferase (EC 2.8.2.13) is an enzyme that catalyzes the chemical reaction

3'-phosphoadenylyl sulfate + galactosylsphingosine adenosine 3',5'-bisphosphate + psychosine sulfate

Thus, the two substrates of this enzyme are 3'-phosphoadenylyl sulfate and galactosylsphingosine, whereas its two products are adenosine 3',5'-bisphosphate and psychosine sulfate.

This enzyme belongs to the family of transferases, specifically the sulfotransferases, which transfer sulfur-containing groups. The systematic name of this enzyme class is 3'-phosphoadenylyl-sulfate:galactosylsphingosine sulfotransferase. Other names in common use include PAPS:psychosine sulphotransferase, and 3'-phosphoadenosine 5'-phosphosulfate-psychosine sulphotransferase.

[edit] References

• IUBMB entry for 2.8.2.13
• BRENDA references for 2.8.2.13 (Recommended.)
• PubMed references for 2.8.2.13
• PubMed Central references for 2.8.2.13
• Google Scholar references for 2.8.2.13
• Nussbaum JL, Mandel P (1972). "Enzymic synthesis of psychosine sulphate". J. Neurochem. 19: 1789–802. doi:10.1111/j.1471-4159.1972.tb06224.x. PMID 5042474. 

[edit] External links

The CAS registry number for this enzyme class is 37259-76-0.

• IUBMB entry for 2.8.2.13

• KEGG entry for 2.8.2.13

• BRENDA entry for 2.8.2.13

• NiceZyme view of 2.8.2.13

• EC2PDB: PDB structures for 2.8.2.13

• PRIAM entry for 2.8.2.13

• PUMA2 entry for 2.8.2.13

• IntEnz: Integrated Enzyme entry for 2.8.2.13

• MetaCyc entry for 2.8.2.13

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0050226: psychosine sulfotransferase

• AMIGO entry for GO code 0050226: psychosine sulfotransferase