PSMD14

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Proteasome (prosome, macropain) 26S subunit, non-ATPase, 14
Identifiers
Symbol(s) PSMD14; PAD1; POH1; rpn11
External IDs OMIM: 607173 MGI: 1913284 HomoloGene: 4240
RNA expression pattern

More reference expression data
Orthologs
Human Mouse
Entrez 10213 59029
Ensembl ENSG00000115233 ENSMUSG00000026914
Uniprot O00487 Q3UD26
Refseq NM_005805 (mRNA)
NP_005796 (protein)		 NM_021526 (mRNA)
NP_067501 (protein)
Location Chr 2: 161.87 - 161.98 Mb Chr 2: 61.51 - 61.6 Mb
Pubmed search [1] [2]

Proteasome (prosome, macropain) 26S subunit, non-ATPase, 14, also known as PSMD14, is a human gene.[1]

POH1 (pad one homolog-1) is a component of the 26S proteasome, a multiprotein complex that degrades proteins targeted for destruction by the ubiquitin pathway (Spataro et al., 1997).[supplied by OMIM][1]

[edit] References

  1. ^ a b Entrez Gene: PSMD14 proteasome (prosome, macropain) 26S subunit, non-ATPase, 14.

[edit] Further reading

  • Spataro V, Toda T, Craig R, et al. (1997). "Resistance to diverse drugs and ultraviolet light conferred by overexpression of a novel human 26 S proteasome subunit.". J. Biol. Chem. 272 (48): 30470–5. PMID 9374539. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039. 
  • Ambroggio XI, Rees DC, Deshaies RJ (2006). "JAMM: a metalloprotease-like zinc site in the proteasome and signalosome.". PLoS Biol. 2 (1): E2. doi:10.1371/journal.pbio.0020002. PMID 14737182. 
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334. 
  • Rush J, Moritz A, Lee KA, et al. (2005). "Immunoaffinity profiling of tyrosine phosphorylation in cancer cells.". Nat. Biotechnol. 23 (1): 94–101. doi:10.1038/nbt1046. PMID 15592455. 
  • Nabhan JF, Ribeiro P (2006). "The 19 S proteasomal subunit POH1 contributes to the regulation of c-Jun ubiquitination, stability, and subcellular localization.". J. Biol. Chem. 281 (23): 16099–107. doi:10.1074/jbc.M512086200. PMID 16569633. 
  • Gallery M, Blank JL, Lin Y, et al. (2007). "The JAMM motif of human deubiquitinase Poh1 is essential for cell viability.". Mol. Cancer Ther. 6 (1): 262–8. doi:10.1158/1535-7163.MCT-06-0542. PMID 17237285. 
  • Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry.". Mol. Syst. Biol. 3: 89. doi:10.1038/msb4100134. PMID 17353931. 
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