Talk:Protein targeting

From Wikipedia, the free encyclopedia

	MCB Portal This article is within the scope of the Molecular and Cellular Biology WikiProject. To participate, visit the WikiProject for more information. The WikiProject's current monthly collaboration is focused on improving Restriction enzyme.
Start	This article has been rated as Start-Class on the assessment scale.
Top	This article is on a subject of Top-importance within molecular and cellular biology.
Article Grading: The following comments were left by the quality and importance raters: (edit · history · refresh · how to use this template) Changed rating to "top" as high school/SAT Biology content and overview of important mechanism in cell biology - tameeria 20:59, 18 February 2007 (UTC)

[edit] Bacterial targeting

This section is woefully inadequate. Some things that I can't flesh out right now, but that should be mentioned (at the very least), include:

• SRP recognition vs. secB recognition of signal sequence
• The SecYEG translocon
• Targeting to the periplasm and outer membrane in gram negative bacteria

Josh 10:04, 15 December 2006 (UTC)

[edit] NES and NLS should not be merged to this entry

I don't think that the NES and NLS entries should be merged to this site. Transportation in and out of the nucleus is a reversible process, which is tightly regulated. In this entry "protein targeting" is defined as a processes which transport a protein to its appropriate position, a process which is irriversible. I don't think that all active transport of proteins should regarded as proteins targeting. User:Hededam 16:41, 23 Nov 2006

Do not merge. I agree with Hededam's reasoning. Nuclear proteins are often regulated by changing their localization in response to a signal, which is a pretty big topic to include in a merged article and doesn't really apply to general protein targeting. Josh 08:19, 15 December 2006 (UTC)

[edit] "errors can lead to diseases."

A list would be interesting. 76.111.8.39 (talk) 19:16, 10 December 2007 (UTC)