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Article Grading: The following comments were left by the quality and importance raters: (edit · history · refresh · how to use this template) high school/SAT biology content and important MCB overview/intro to transcription, translation etc.; changed rating from high to top - tameeria 15:17, 18 February 2007 (UTC)

following translation you are bound to run in circles. translation (genetic) really deserves a page of it's own. Kku 11:43 Jan 10, 2003 (UTC)

Contents 1 Post-translational modification 2 Post-translational modification 2.1 needs pictures 2.2 Prokaryotic protein synthesis 2.3 diagram incorrect 2.4 not understandable 2.5 Translation? 2.6 Strange use of words 2.7 copyvio

[edit] Post-translational modification

I can see how you'd be confused, Dominus, but I can also understand why the article would be worded that way, as there are different post-translational modification processes involving different chemical/structural changes, and if a protein is not chemically modified, then PTMs are irrelevant. Perhaps it would clarify things to word the statement as follows: "Proteins may undergo post-translational modification, including the formation of disulfide bridges or attachment of any of a number of biochemical functional groups..." Rena Silverman 16:04, 17 September 2007 (UTC)

[edit] Post-translational modification

The article says:

Many proteins undergo post-translational modification.

Don't all proteins undergo post-translational modification to remove the methionine unit that is always present at the initial end of the strand after it is manufactured by the ribosome? -- Dominus 16:07, 9 May 2004 (UTC)

[edit] needs pictures

Some pictures would really help this article. --67.80.171.173 20:21, 5 June 2006 (UTC)

I have to agree that some pictures or even animated diagrams would help--ManInStone 10:07, 6 July 2007 (UTC)

By now, ANYTHING WOULD HELP!!!!!!!! --Heero Kirashami (talk) 06:29, 29 November 2007 (UTC)

[edit] Prokaryotic protein synthesis

This article should contain much more information on the differences between prokaryote and eukaryote protein synthesis. One is left with the impression that all RNA synthesis (transcription) produces mRNA transcripts with polyA tails. There is no mention of how transcription and translation are linked in prokaryotes. There also needs to be mention of polycistronic organisation in prokaryotes and monocistronic organisation in eukaryotes. Also mention that there are no introns in prokaryotes could be made. Anyone up for it?--Alun 05:34, 13 May 2005 (UTC)

[edit] diagram incorrect

not being a clever biologist myself at my GCSEs, i couldn't help but notice that the diagram "The chemical process of connecting two amino acids resulting in a dipeptide and a water molecule" was incorrect.

Water, being H²O, is connected up as H-O-H, but is connected as a right angle, so more like

H

|

O -- H

Thanks

Stwalkerster 19:14, 20 September 2006 (UTC)

Water is a lot more than the diagram above as well. For the purpose of this article, a representation of HOH is adequate, as we are more interested in the nature of the dipeptide.

[edit] not understandable

this article and the ones under it like transcription are not understandable to me, a scientist not trained in biology. they assume more knowledge than many interested readers will have. they jump right into arcane technical details without giving upfront motivation. --Rmalloy 04:46, 8 October 2006 (UTC)

hey, you're a scientist not trained in biology. me, I'm just a smart minor who is trying to understand this stuff.--Heero Kirashami (talk) 06:31, 29 November 2007 (UTC)

i have been trying to figure outt how long this process is. its an important part to this article. if any1 knows plz let me no. my email is ammenworb@gmail.com thx<3 —Preceding unsigned comment added by 71.172.235.100 (talk) 21:53, 6 March 2008 (UTC)

[edit] Translation?

Why doesn't this article contain information about Translation? It seems to be that this is the most important step of protein biosynthesis (that is to say, it is the step that immediately results in a protein). Malignon 16:25, 8 March 2007 (UTC)

I just added a section on translation... but it may be a bit long and probably needs some editing... if someone could look it over please! :) -ComCC 01:38, 18 April 2007 (UTC)

[edit] Strange use of words

What is the scientific background behind the sentence; "The amino acids are then loaded onto tRNA trains for use in the process of journeying forth to the world beyond."? I think this should be removed. —Preceding unsigned comment added by Lozzaaa (talk • contribs) 13:44, 24 February 2008 (UTC)

[edit] copyvio

Since the translation section was in odd language and was signed with a book and publisher, assuming copyvio - quick fix replaced with lead section from Translation (biology) Leevanjackson (talk) 01:48, 24 March 2008 (UTC)