Protein SET

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SET translocation (myeloid leukemia-associated)
PDB rendering based on 2e50.
Available structures: 2e50
Identifiers
Symbol(s) SET; 2PP2A; I2PP2A; IGAAD; PHAPII; TAF-IBETA
External IDs OMIM: 600960 MGI: 1860267 HomoloGene: 55707
Orthologs
Human Mouse
Entrez 6418 56086


Uniprot Q01105 n/a
Refseq NM_003011 (mRNA)
NP_003002 (protein)		 XM_978154 (mRNA)
XP_983248 (protein)
Pubmed search [1] [2]

SET translocation (myeloid leukemia-associated), also known as SET, is a human gene.[1]


[edit] References

  1. ^ Entrez Gene: SET SET translocation (myeloid leukemia-associated).

[edit] Further reading

  • von Lindern M, van Baal S, Wiegant J, et al. (1992). "Can, a putative oncogene associated with myeloid leukemogenesis, may be activated by fusion of its 3' half to different genes: characterization of the set gene.". Mol. Cell. Biol. 12 (8): 3346–55. PMID 1630450. 
  • Nagata K, Kawase H, Handa H, et al. (1995). "Replication factor encoded by a putative oncogene, set, associated with myeloid leukemogenesis.". Proc. Natl. Acad. Sci. U.S.A. 92 (10): 4279–83. PMID 7753797. 
  • Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.". Gene 138 (1-2): 171–4. PMID 8125298. 
  • Adachi Y, Pavlakis GN, Copeland TD (1994). "Identification of in vivo phosphorylation sites of SET, a nuclear phosphoprotein encoded by the translocation breakpoint in acute undifferentiated leukemia.". FEBS Lett. 340 (3): 231–5. PMID 8131851. 
  • Vaesen M, Barnikol-Watanabe S, Götz H, et al. (1994). "Purification and characterization of two putative HLA class II associated proteins: PHAPI and PHAPII.". Biol. Chem. Hoppe-Seyler 375 (2): 113–26. PMID 8192856. 
  • Adachi Y, Pavlakis GN, Copeland TD (1994). "Identification and characterization of SET, a nuclear phosphoprotein encoded by the translocation break point in acute undifferentiated leukemia.". J. Biol. Chem. 269 (3): 2258–62. PMID 8294483. 
  • Li M, Makkinje A, Damuni Z (1996). "The myeloid leukemia-associated protein SET is a potent inhibitor of protein phosphatase 2A.". J. Biol. Chem. 271 (19): 11059–62. PMID 8626647. 
  • Adler HT, Nallaseth FS, Walter G, Tkachuk DC (1997). "HRX leukemic fusion proteins form a heterocomplex with the leukemia-associated protein SET and protein phosphatase 2A.". J. Biol. Chem. 272 (45): 28407–14. PMID 9353299. 
  • Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.". Gene 200 (1-2): 149–56. PMID 9373149. 
  • Carlson SG, Eng E, Kim EG, et al. (1999). "Expression of SET, an inhibitor of protein phosphatase 2A, in renal development and Wilms' tumor.". J. Am. Soc. Nephrol. 9 (10): 1873–80. PMID 9773788. 
  • Brennan CM, Gallouzi IE, Steitz JA (2000). "Protein ligands to HuR modulate its interaction with target mRNAs in vivo.". J. Cell Biol. 151 (1): 1–14. PMID 11018049. 
  • Shikama N, Chan HM, Krstic-Demonacos M, et al. (2000). "Functional interaction between nucleosome assembly proteins and p300/CREB-binding protein family coactivators.". Mol. Cell. Biol. 20 (23): 8933–43. PMID 11073993. 
  • Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination.". Genome Res. 10 (11): 1788–95. PMID 11076863. 
  • Seo SB, McNamara P, Heo S, et al. (2001). "Regulation of histone acetylation and transcription by INHAT, a human cellular complex containing the set oncoprotein.". Cell 104 (1): 119–30. PMID 11163245. 
  • Minakuchi M, Kakazu N, Gorrin-Rivas MJ, et al. (2001). "Identification and characterization of SEB, a novel protein that binds to the acute undifferentiated leukemia-associated protein SET.". Eur. J. Biochem. 268 (5): 1340–51. PMID 11231286. 
  • Beresford PJ, Zhang D, Oh DY, et al. (2001). "Granzyme A activates an endoplasmic reticulum-associated caspase-independent nuclease to induce single-stranded DNA nicks.". J. Biol. Chem. 276 (46): 43285–93. doi:10.1074/jbc.M108137200. PMID 11555662. 
  • Gallouzi IE, Brennan CM, Steitz JA (2001). "Protein ligands mediate the CRM1-dependent export of HuR in response to heat shock.". RNA 7 (9): 1348–61. PMID 11565755. 
  • Qu D, Li Q, Lim HY, et al. (2002). "The protein SET binds the neuronal Cdk5 activator p35nck5a and modulates Cdk5/p35nck5a activity.". J. Biol. Chem. 277 (9): 7324–32. doi:10.1074/jbc.M107270200. PMID 11741927. 
  • Fan Z, Beresford PJ, Zhang D, Lieberman J (2002). "HMG2 interacts with the nucleosome assembly protein SET and is a target of the cytotoxic T-lymphocyte protease granzyme A.". Mol. Cell. Biol. 22 (8): 2810–20. PMID 11909973. 
  • Cervoni N, Detich N, Seo SB, et al. (2002). "The oncoprotein Set/TAF-1beta, an inhibitor of histone acetyltransferase, inhibits active demethylation of DNA, integrating DNA methylation and transcriptional silencing.". J. Biol. Chem. 277 (28): 25026–31. doi:10.1074/jbc.M202256200. PMID 11978794. 
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