Talk:Primaquine

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related to Chloroquine

[edit] Radical cure

I have removed the bits about primaquine not being effective against the erythrocytic stages of malaria as untrue. Primaquine is very effective against the erythrocytic stages of malaria, but is always given with chloroquine because the effect against hypnozoites is potentiated by quinine or chloroquine. I have referenced this statement in the article. --Gak 18:04, 13 January 2007 (UTC)


It is not clear from this context whether it is necessary to take chloroquine with primaquine once the blood stage treatment has completed. For example, suppose one finished chloroquine 10 days ago and no longer has symptoms or re-exposure. Does one then need to take more chloroquine to potentiate the primaquine in killing liver hypnozoites? And if this would be needed in this case, why would more chloroquine not be needed after 10 days of treatment because presumably the chloroquine is mostly gone from the plasma after 11 days. —Preceding unsigned comment added by 67.180.196.83 (talk) 07:09, 10 September 2007 (UTC)