Talk:Pregabalin

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[edit] Anxiety

I would considerably appreciate further details regarding Lyrica's efficacy in treating anxiety, as well as more information regarding Pfizer's effort to get the drug indicated for the treatment of the aforesaid disorder.

  • Well, it seems the FDA was not very excited, so the question is academic (unless someone is willing to prescribe this off-label, which is not recommended). Perhaps Google will help here. JFW | T@lk 21:31, 9 January 2006 (UTC)
  • If you are interested in scientific articles and papers, then try searching on Google Scholar or PubMed. Most of this stuff will have been peer-reviewed, which is better than the average web article. However be aware that some studies are very small scale and there is a limit to what you can get from just an abstract if the full paper isn't free. Regarding approval – it looks like the FDA and Pfizer are keeping quiet about the reasons why it failed. Note: it was General anxiety disorder that they applied for, not other forms of anxiety. --Colin 23:25, 9 January 2006 (UTC)
  • Pfizer originally tried to get Lyrica approved as a 'neuromodulator' - i.e. a drug that stopped seizures, controlled anxiety, reduced pain, and was indicated for the modulation of every other neuro as well. The FDA bounced that in a heartbeat. -Ikkyu2 15:37, 10 January 2006 (UTC)
  • As has been noted in the article, Lyrica has received a positive opinion from the European Medicines Agency/CHMP for the treatment of generalized anxiety disorder in adults. Zzorse 17:08, 5 March 2006 (UTC)

[edit] Possible side effects

Does the article need all those potential side effects listed? Compare to the style used in other anticonvulsant articles. Zzorse 17:08, 5 March 2006 (UTC)

This matter was addressed quite a while back by another user, thank you. Zzorse 20:59, 21 March 2007 (UTC)

[edit] controlled substance?

Is Lyrica a controlled substance, if so why? and what drug class (schedule) is it in- is it a benzodiazipine? I can not find any information on this. thanks —Preceding unsigned comment added by 71.100.201.101 (talk) 15:54, 18 December 2007 (UTC)

Clicking 'Legal status' in the infobox will start you on a somewhat confusing path that eventually leads here. --CliffC (talk) 19:14, 18 December 2007 (UTC)

[edit] Pregabalin in Lyrica

We are searching for another medication in place of Lyrica because of the swelling it is causing my patient which is a quadriplegic. If pregabalin is the main ingrediant, shouldnt the doctor take this more seriously and change his medication? The Lyrica does work for his pain but the side affects are too much. Any suggestions or knowledge of another medication without the side affects of swelling and nautiousness? Please email me with any advice at xxcajunspicegirlxx@hotmail.com.........Thank You.....Smiles...R.M.B.

[edit] I have experienced lyrica

i have tried Lyrica and it is very strong.It is definitally stronger than gabapentian which I have been on for years but,because of the Lyrica and the gabapentian being used at the same time I had an adverse effect.I began to hallucinate and become very unstable.So much so that i could not be home alone someone had to stay with me 24/7.so be careful —Preceding unsigned comment added by Moonboo30 (talk • contribs) 00:54, 31 March 2008 (UTC)

[edit] off-label use in Bipolar disease treatment

Is it possible? Could someone write some info about it?
Thankyou so much! 87.117.41.250 (talk) 23:28, 5 June 2008 (UTC)