Prephenic acid
From Wikipedia, the free encyclopedia
| Prephenic acid | |
|---|---|
| Identifiers | |
| CAS number | [126-49-8] |
| PubChem | |
| MeSH | |
| SMILES | C1=CC(C=CC1O)(CC(=O)C(=O)O)C(=O)O |
| Properties | |
| Molecular formula | C10H10O6 |
| Molar mass | 226.183 |
| Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) Infobox disclaimer and references |
|
Prephenic acid, more commonly known by its anionic form prephenate, is an intermediate in the biosynthesis of the aromatic amino acids phenylalanine and tyrosine.
It is synthesized by a [3,3]-sigmatropic Claisen rearrangement of chorismate.[1][2]
[edit] References
- ^ Helmut Goerisch (1978). "On the mechanism of the chorismate mutase reaction". Biochemistry: 3700. doi:.
- ^ Peter Kast, Yadu B. Tewari, Olaf Wiest, Donald Hilvert, Kendall N. Houk, and Robert N. Goldberg (1997). "Thermodynamics of the Conversion of Chorismate to Prephenate: Experimental Results and Theoretical Predictions". J. Phys. Chem. B 101 (50): 10976–10982. doi:.

