Prenylcysteine oxidase

From Wikipedia, the free encyclopedia

In enzymology, a prenylcysteine oxidase (EC 1.8.3.5) is an enzyme that catalyzes the chemical reaction

an S-prenyl-L-cysteine + O₂ + H₂O a prenal + L-cysteine + H₂O₂

The 3 substrates of this enzyme are S-prenyl-L-cysteine, O₂, and H₂O, whereas its 3 products are prenal, L-cysteine, and H₂O₂.

This enzyme belongs to the family of oxidoreductases, specifically those acting on a sulfur group of donors with oxygen as acceptor. The systematic name of this enzyme class is S-prenyl-L-cysteine:oxygen oxidoreductase. This enzyme is also called prenylcysteine lyase.

[edit] References

• IUBMB entry for 1.8.3.5
• BRENDA references for 1.8.3.5 (Recommended.)
• PubMed references for 1.8.3.5
• PubMed Central references for 1.8.3.5
• Google Scholar references for 1.8.3.5
• Zhang L, Tschantz WR, Casey PJ (1997). "Isolation and characterization of a prenylcysteine lyase from bovine brain". J. Biol. Chem. 272: 23354–9. doi:10.1074/jbc.272.37.23354. PMID 9287348. 
• Tschantz WR, Digits JA, Pyun HJ, Coates RM, Casey PJ (2001). "Lysosomal prenylcysteine lyase is a FAD-dependent thioether oxidase". J. Biol. Chem. 276: 2321–4. doi:10.1074/jbc.C000616200. PMID 11078725. 

[edit] External links

• IUBMB entry for 1.8.3.5

• KEGG entry for 1.8.3.5

• BRENDA entry for 1.8.3.5

• NiceZyme view of 1.8.3.5

• EC2PDB: PDB structures for 1.8.3.5

• PRIAM entry for 1.8.3.5

• PUMA2 entry for 1.8.3.5

• IntEnz: Integrated Enzyme entry for 1.8.3.5

• MetaCyc entry for 1.8.3.5

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0001735: prenylcysteine oxidase

• AMIGO entry for GO code 0001735: prenylcysteine oxidase