Precorrin-3B C17-methyltransferase

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In enzymology, a precorrin-3B C17-methyltransferase (EC 2.1.1.131) is an enzyme that catalyzes the chemical reaction

S-adenosyl-L-methionine + precorrin-3B $\rightleftharpoons$ S-adenosyl-L-homocysteine + precorrin-4

Thus, the two substrates of this enzyme are S-adenosyl methionine and precorrin 3B, whereas its two products are S-adenosylhomocysteine and precorrin 4.

This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is S-adenosyl-L-methionine:precorrin-3B C17-methyltransferase. Other names in common use include precorrin-3 methyltransferase, and CobJ. This enzyme participates in porphyrin and chlorophyll metabolism.

[edit] References

IUBMB entry for 2.1.1.131
BRENDA references for 2.1.1.131 (Recommended.)
PubMed references for 2.1.1.131
PubMed Central references for 2.1.1.131
Google Scholar references for 2.1.1.131
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Debussche L, Thibaut D, Cameron B, Crouzet J, Blanche F (1993). "Biosynthesis of the corrin macrocycle of coenzyme B12 in Pseudomonas denitrificans". J. Bacteriol. 175: 7430–40. PMID 8226690.