PPIG (gene)

From Wikipedia, the free encyclopedia

Peptidylprolyl isomerase G (cyclophilin G)

PDB rendering based on 2gw2.

Available structures: 2gw2

Identifiers

Symbol(s)

PPIG; CARS-Cyp; CYP; MGC133241; SRCyp

External IDs

OMIM: 606093 MGI: 2445173 HomoloGene: 3520

Gene ontology
Molecular Function:	• peptidyl-prolyl cis-trans isomerase activity • cyclosporin A binding • isomerase activity
Cellular Component:	• nucleus • nucleoplasm
Biological Process:	• protein folding • RNA splicing

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

n/a

Refseq

NM_004792 (mRNA)
NP_004783 (protein)

XM_001003390 (mRNA)
XP_001003390 (protein)

Location

Chr 2: 170.15 - 170.2 Mb

Chr 2: 69.52 - 69.56 Mb

Pubmed search

[1]

[2]

Peptidylprolyl isomerase G (cyclophilin G), also known as PPIG, is a human gene.^[1]

[edit] References

^ Entrez Gene: PPIG peptidylprolyl isomerase G (cyclophilin G).

[edit] Further reading

Nestel FP, Colwill K, Harper S, et al. (1997). "RS cyclophilins: identification of an NK-TR1-related cyclophilin.". Gene 180 (1-2): 151-5. PMID 8973360.
Bourquin JP, Stagljar I, Meier P, et al. (1997). "A serine/arginine-rich nuclear matrix cyclophilin interacts with the C-terminal domain of RNA polymerase II.". Nucleic Acids Res. 25 (11): 2055-61. PMID 9153302.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
Dubourg B, Kamphausen T, Weiwad M, et al. (2004). "The human nuclear SRcyp is a cell cycle-regulated cyclophilin.". J. Biol. Chem. 279 (21): 22322-30. doi:10.1074/jbc.M400736200. PMID 15016823.
Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins.". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130-5. doi:10.1073/pnas.0404720101. PMID 15302935.
Jin J, Smith FD, Stark C, et al. (2004). "Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization.". Curr. Biol. 14 (16): 1436-50. doi:10.1016/j.cub.2004.07.051. PMID 15324660.
Lin CL, Leu S, Lu MC, Ouyang P (2004). "Over-expression of SR-cyclophilin, an interaction partner of nuclear pinin, releases SR family splicing factors from nuclear speckles.". Biochem. Biophys. Res. Commun. 321 (3): 638-47. doi:10.1016/j.bbrc.2004.07.013. PMID 15358154.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334.
Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network.". Nature 437 (7062): 1173-8. doi:10.1038/nature04209. PMID 16189514.
Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.". Cell 127 (3): 635-48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.