Talk:Position-specific scoring matrix

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This article could be improved by adding examples, such as PSI-BLAST and motif/consensus pattern profiles. - tameeria (talk) 23:17, 8 December 2007 (UTC)

[edit] reference translation

Does anyone have an English translation of this article that is referenced: Aleksandrushkina NI, Egorova LA. "[Nucleotide makeup of the DNA of thermophilic bacteria of the genus Thermus.]" Mikrobiologiia. Mar 1978, 47(2):250-2.

I have believed that my thesis work, part of which was published here:

 Use of the 'Perceptron' algorithm to distinguish translational initiation sites in E. coli.
 Stormo GD, Schneider TD, Gold L, Ehrenfeucht A.
 Nucleic Acids Res. 1982 May 11;10(9):2997-3011.

was the introduction of position weight matrices (or PWMs, PSSMs, etc) to the field of biological sequence analysis. If this Russian paper actually used such matrices that would predate my work, but I have not seen this reference before. Gary Stormo —Preceding unsigned comment added by 128.252.234.247 (talk) 14:50, 27 February 2008 (UTC)