Poly ICLC

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Poly ICLC
Systematic (IUPAC) name
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Identifiers
CAS number  ?
ATC code L03AX08
PubChem  ?
Chemical data
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Metabolism  ?
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Poly ICLC is an immunostimulant.

It consists of carboxymethylcellulose, polyinosinic-polycytidylic acid, and poly-L-lysine double-stranded RNA.[1]

It is a ligand for toll like receptor-3.[2]

[edit] References

  1. ^ Definition of poly ICLC - National Cancer Institute Drug Dictionary. Retrieved on 2007-11-13.
  2. ^ Zhu X, Nishimura F, Sasaki K, et al (2007). "Toll like receptor-3 ligand poly-ICLC promotes the efficacy of peripheral vaccinations with tumor antigen-derived peptide epitopes in murine CNS tumor models". Journal of translational medicine 5: 10. doi:10.1186/1479-5876-5-10. PMID 17295916. 
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Immunomodulators - immunostimulants (L03)
Colony stimulating factors
Interferons
alpha: Interferon alpha natural - Interferon alpha-2a/Peginterferon alpha-2a - Interferon alpha-2b/Peginterferon alpha-2b - Interferon alpha-n1 - Interferon alphacon-1

beta: Interferon beta natural - Interferon beta-1a - Interferon beta-1b

Interferon gamma
Interleukins
Other cytokines and endogenous immunostimulants
Exogenous

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