Poly(alpha-L-guluronate) lyase
From Wikipedia, the free encyclopedia
In enzymology, a poly(alpha-L-guluronate) lyase (EC 4.2.2.11) is an enzyme that catalyzes the chemical reaction
- Eliminative cleavage of polysaccharides containing a terminal alpha-L-guluronate group, to give oligosaccharides with 4-deoxy-alpha-L-erythro-hex-4-enuronosyl groups at their non-reducing ends
This enzyme belongs to the family of lyases, specifically those carbon-oxygen lyases acting on polysaccharides. The systematic name of this enzyme class is poly(alpha-L-1,4-guluronide) exo-lyase. Other names in common use include alginase II, guluronate lyase, L-guluronan lyase, L-guluronate lyase, poly-alpha-L-guluronate lyase, and polyguluronate-specific alginate lyase.
Contents |
[edit] Structural studies
As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code 1UAI.
[edit] References
- IUBMB entry for 4.2.2.11
- BRENDA references for 4.2.2.11 (Recommended.)
- PubMed references for 4.2.2.11
- PubMed Central references for 4.2.2.11
- Google Scholar references for 4.2.2.11
- Boyd J, Turvey JR (1977). "Isolation of poly-alpha-L-guluronate lyase from Klebsiella aerogenes". Carbohydr. Res. 57: 163–71. doi:. PMID 332364.
- Davidson IW, Sutherland IW, Lawson CJ (1976). "Purification and properties of an alginate lyase from a marine bacterium". Biochem. J. 159: 707–13. PMID 1008828.
[edit] External links
-
- The CAS registry number for this enzyme class is 64177-88-4.
[edit] Gene Ontology (GO) codes
 |
This EC 4.2 enzyme-related article is a stub. You can help Wikipedia by expanding it. |
