POLR3C

From Wikipedia, the free encyclopedia

Polymerase (RNA) III (DNA directed) polypeptide C (62kD)

Identifiers

POLR3C; RPC3; RPC62

External IDs

MGI: 1921664 HomoloGene: 38185

Gene ontology
Molecular Function:	• DNA binding • DNA-directed RNA polymerase activity • transferase activity
Cellular Component:	• nucleus • DNA-directed RNA polymerase III complex
Biological Process:	• transcription • regulation of transcription from RNA polymerase III promoter

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_006468 (mRNA)
NP_006459 (protein)

XM_131049 (mRNA)
XP_131049 (protein)

Location

Chr 1: 144.3 - 144.32 Mb

Chr 3: 96.8 - 96.81 Mb

Pubmed search

[1]

[2]

Polymerase (RNA) III (DNA directed) polypeptide C (62kD), also known as POLR3C, is a human gene.^[1]

[edit] References

^ Entrez Gene: POLR3C polymerase (RNA) III (DNA directed) polypeptide C (62kD).

[edit] Further reading

Jang KL, Collins MK, Latchman DS (1992). "The human immunodeficiency virus tat protein increases the transcription of human Alu repeated sequences by increasing the activity of the cellular transcription factor TFIIIC.". J. Acquir. Immune Defic. Syndr. 5 (11): 1142-7. PMID 1403646.
Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.". Gene 138 (1-2): 171-4. PMID 8125298.
Wang Z, Roeder RG (1997). "Three human RNA polymerase III-specific subunits form a subcomplex with a selective function in specific transcription initiation.". Genes Dev. 11 (10): 1315-26. PMID 9171375.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.". Gene 200 (1-2): 149-56. PMID 9373149.
Hsieh YJ, Wang Z, Kovelman R, Roeder RG (1999). "Cloning and characterization of two evolutionarily conserved subunits (TFIIIC102 and TFIIIC63) of human TFIIIC and their involvement in functional interactions with TFIIIB and RNA polymerase III.". Mol. Cell. Biol. 19 (7): 4944-52. PMID 10373544.
Hsieh YJ, Kundu TK, Wang Z, et al. (1999). "The TFIIIC90 subunit of TFIIIC interacts with multiple components of the RNA polymerase III machinery and contains a histone-specific acetyltransferase activity.". Mol. Cell. Biol. 19 (11): 7697-704. PMID 10523658.
Kuwana M, Kimura K, Kawakami Y (2002). "Identification of an immunodominant epitope on RNA polymerase III recognized by systemic sclerosis sera: application to enzyme-linked immunosorbent assay.". Arthritis Rheum. 46 (10): 2742-7. doi:10.1002/art.10521. PMID 12384934.
Hu P, Wu S, Sun Y, et al. (2002). "Characterization of human RNA polymerase III identifies orthologues for Saccharomyces cerevisiae RNA polymerase III subunits.". Mol. Cell. Biol. 22 (22): 8044-55. PMID 12391170.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334.