POLR1E

From Wikipedia, the free encyclopedia

Polymerase (RNA) I polypeptide E, 53kDa

Identifiers

POLR1E; PRAF1; FLJ13390; FLJ13970; PAF53; RP11-405L18.3

External IDs

MGI: 1929022 HomoloGene: 41486

Gene ontology
Molecular Function:	• DNA binding • DNA-directed RNA polymerase activity • protein binding • transferase activity
Cellular Component:	• nucleus • nucleolus
Biological Process:	• transcription • rRNA transcription

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_022490 (mRNA)
NP_071935 (protein)

NM_022811 (mRNA)
NP_073722 (protein)

Location

Chr 9: 37.48 - 37.49 Mb

Chr 4: 45.04 - 45.05 Mb

Pubmed search

[1]

[2]

Polymerase (RNA) I polypeptide E, 53kDa, also known as POLR1E, is a human gene.^[1]

[edit] References

^ Entrez Gene: POLR1E polymerase (RNA) I polypeptide E, 53kDa.

[edit] Further reading

Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.". Gene 138 (1-2): 171-4. PMID 8125298.
Hanada K, Song CZ, Yamamoto K, et al. (1996). "RNA polymerase I associated factor 53 binds to the nucleolar transcription factor UBF and functions in specific rDNA transcription.". EMBO J. 15 (9): 2217-26. PMID 8641287.
Seither P, Zatsepina O, Hoffmann M, Grummt I (1997). "Constitutive and strong association of PAF53 with RNA polymerase I.". Chromosoma 106 (4): 216-25. PMID 9254723.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.". Gene 200 (1-2): 149-56. PMID 9373149.
Voit R, Grummt I (2002). "Phosphorylation of UBF at serine 388 is required for interaction with RNA polymerase I and activation of rDNA transcription.". Proc. Natl. Acad. Sci. U.S.A. 98 (24): 13631-6. doi:10.1073/pnas.231071698. PMID 11698641.
Scherl A, Couté Y, Déon C, et al. (2003). "Functional proteomic analysis of human nucleolus.". Mol. Biol. Cell 13 (11): 4100-9. doi:10.1091/mbc.E02-05-0271. PMID 12429849.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
Bjerregaard B, Wrenzycki C, Strejcek F, et al. (2004). "Expression of nucleolar-related proteins in porcine preimplantation embryos produced in vivo and in vitro.". Biol. Reprod. 70 (4): 867-76. doi:10.1095/biolreprod.103.021683. PMID 14585813.
Baran V, Pavlok A, Bjerregaard B, et al. (2004). "Immunolocalization of upstream binding factor and pocket protein p130 during final stages of bovine oocyte growth.". Biol. Reprod. 70 (4): 877-86. doi:10.1095/biolreprod.103.018408. PMID 14613906.
Bjerregaard B, Wrenzycki C, Philimonenko VV, et al. (2004). "Regulation of ribosomal RNA synthesis during the final phases of porcine oocyte growth.". Biol. Reprod. 70 (4): 925-35. doi:10.1095/biolreprod.103.020941. PMID 14627545.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40-5. doi:10.1038/ng1285. PMID 14702039.
Bouwmeester T, Bauch A, Ruffner H, et al. (2004). "A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway.". Nat. Cell Biol. 6 (2): 97-105. doi:10.1038/ncb1086. PMID 14743216.
Humphray SJ, Oliver K, Hunt AR, et al. (2004). "DNA sequence and analysis of human chromosome 9.". Nature 429 (6990): 369-74. doi:10.1038/nature02465. PMID 15164053.
Yamamoto K, Yamamoto M, Hanada K, et al. (2004). "Multiple protein-protein interactions by RNA polymerase I-associated factor PAF49 and role of PAF49 in rRNA transcription.". Mol. Cell. Biol. 24 (14): 6338-49. doi:10.1128/MCB.24.14.6338-6349.2004. PMID 15226435.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334.
Percipalle P, Fomproix N, Cavellán E, et al.. "The chromatin remodelling complex WSTF-SNF2h interacts with nuclear myosin 1 and has a role in RNA polymerase I transcription.". EMBO Rep. 7 (5): 525-30. doi:10.1038/sj.embor.7400657. PMID 16514417.
Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry.". Mol. Syst. Biol. 3: 89. doi:10.1038/msb4100134. PMID 17353931.