PNRC1

From Wikipedia, the free encyclopedia

Proline-rich nuclear receptor coactivator 1

Identifiers

PNRC1; PRR2; B4-2; PNAS-145; PROL2; RP11-63L7.5

External IDs

OMIM: 606714 MGI: 1917838 HomoloGene: 4960

Gene ontology
Molecular Function:	• protein binding
Cellular Component:	• nucleus
Biological Process:	• transcription • regulation of transcription, DNA-dependent

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

n/a

Refseq

NM_006813 (mRNA)
NP_006804 (protein)

XM_980235 (mRNA)
XP_985329 (protein)

Location

Chr 6: 89.85 - 89.85 Mb

Chr 4: 33.57 - 33.58 Mb

Pubmed search

[1]

[2]

Proline-rich nuclear receptor coactivator 1, also known as PNRC1, is a human gene.^[1]

[edit] References

^ Entrez Gene: PNRC1 proline-rich nuclear receptor coactivator 1.

[edit] Further reading

Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334.
Zhou D, Chen B, Ye JJ, Chen S (2004). "A novel crosstalk mechanism between nuclear receptor-mediated and growth factor/Ras-mediated pathways through PNRC-Grb2 interaction.". Oncogene 23 (31): 5394-404. doi:10.1038/sj.onc.1207695. PMID 15122321.
Mungall AJ, Palmer SA, Sims SK, et al. (2003). "The DNA sequence and analysis of human chromosome 6.". Nature 425 (6960): 805-11. doi:10.1038/nature02055. PMID 14574404.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
Zhou D, Chen S (2001). "PNRC2 is a 16 kDa coactivator that interacts with nuclear receptors through an SH3-binding motif.". Nucleic Acids Res. 29 (19): 3939-48. PMID 11574675.
Zhou D, Quach KM, Yang C, et al. (2000). "PNRC: a proline-rich nuclear receptor coregulatory protein that modulates transcriptional activation of multiple nuclear receptors including orphan receptors SF1 (steroidogenic factor 1) and ERRalpha1 (estrogen related receptor alpha-1).". Mol. Endocrinol. 14 (7): 986-98. PMID 10894149.
Hsiao PW, Chang C (1999). "Isolation and characterization of ARA160 as the first androgen receptor N-terminal-associated coactivator in human prostate cells.". J. Biol. Chem. 274 (32): 22373-9. PMID 10428808.
Chen J, Liu L, Pohajdak B (1995). "Cloning a cDNA from human NK/T cells which codes for a protein with high proline content.". Biochim. Biophys. Acta 1264 (1): 19-22. PMID 7578250.