Talk:Pleiotropy
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"PKU is totally benign if a diet free from the amino acid is maintained. Depending on the mutation involved, this results in reduced or zero conversion of phenylalanine to tyrosine, and phenylalanine concentrations increase to toxic levels, causing damage at several locations in the body."
This quote is confusing.
[edit] Focus 'Mechanism' on the mechanism, not on PKU
This section should be about how one gene can control several traits. We get started down this road by noting that PKU can cause two unrelated traits: mental retardation and pigmentation. However, there's no explanation of the mechanism for this. The fact that PKU can be benign under certain circumstances is irrelevant.
The entire second paragraph of the Mechanism section, except the first sentence, should be deleted, and replaced with an explanation of how one enzyme can affect both mental retardation and pigmentation.
Asteen 16:06, 14 November 2007 (UTC)
