Plasmalogen synthase

From Wikipedia, the free encyclopedia

In enzymology, a plasmalogen synthase (EC 2.3.1.25) is an enzyme that catalyzes the chemical reaction

acyl-CoA + 1-O-alk-1-enyl-glycero-3-phosphocholine CoA + plasmenylcholine

Thus, the two substrates of this enzyme are acyl-CoA and 1-O-alk-1-enyl-glycero-3-phosphocholine, whereas its two products are CoA and plasmenylcholine.

This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is acyl-CoA:1-O-alk-1-enyl-glycero-3-phosphocholine 2-O-acyltransferase. Other names in common use include lysoplasmenylcholine acyltransferase, O-1-alkenylglycero-3-phosphorylcholine acyltransferase, and 1-alkenyl-glycero-3-phosphorylcholine:acyl-CoA acyltransferase. This enzyme participates in ether lipid metabolism.

[edit] References

• IUBMB entry for 2.3.1.25
• BRENDA references for 2.3.1.25 (Recommended.)
• PubMed references for 2.3.1.25
• PubMed Central references for 2.3.1.25
• Google Scholar references for 2.3.1.25
• Waku K, Lands WE (1968). "Acyl coenzyme A:1-alkenyl-glycero-3-phosphorylcholine acyltransferase action in plasmalogen biosynthesis". J. Biol. Chem. 243: 2654–9. PMID 5689955. 

[edit] External links

The CAS registry number for this enzyme class is 37257-10-6.

• IUBMB entry for 2.3.1.25

• KEGG entry for 2.3.1.25

• BRENDA entry for 2.3.1.25

• NiceZyme view of 2.3.1.25

• EC2PDB: PDB structures for 2.3.1.25

• PRIAM entry for 2.3.1.25

• PUMA2 entry for 2.3.1.25

• IntEnz: Integrated Enzyme entry for 2.3.1.25

• MetaCyc entry for 2.3.1.25

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0050200: plasmalogen synthase

• AMIGO entry for GO code 0050200: plasmalogen synthase